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- Table of Contents
Facts about Ras-related protein Rab-22A.
Required for NGF-mediated endocytosis of NTRK1, and subsequent neurite outgrowth. Binds GTP and GDP and has reduced GTPase activity.
Mouse | |
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Gene Name: | Rab22a |
Uniprot: | P35285 |
Entrez: | 19334 |
Belongs to: |
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small GTPase superfamily |
GTP-binding protein RAB22A; MGC16770; RAB22; Rab-22; RAB22A, member RAS oncogene family; ras-related protein Rab-22A
Mass (kDA):
21.802 kDA
Mouse | |
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Location: | 2 H3-H4|2 97.26 cM |
Sequence: | 2; |
Detected in brain and heart, and at lower levels in lung and spleen.
PMID: 1555775 by Chavrier P., et al. The complexity of the Rab and Rho GTP-binding protein subfamilies revealed by a PCR cloning approach.
PMID: 8126105 by Olkkonen V.M., et al. Molecular cloning and subcellular localization of three GTP-binding proteins of the rab subfamily.