Ropporin-1A Antibodies

AND ROPN1 ELISA kits, Ropporin-1A Proteins

Many biological assays use antibodies to detect Ropporin-1A, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Ropporin-1A in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Ropporin-1A antibodies...

We validate the specificity of these antibodies to Ropporin-1A by testing them on tissues known to express ROPN1 positively and negatively. Browse below to find the ROPN1 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ROPN1 Infographic by Boster Bio

All ROPN1 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-ROPN1 Antibody (Center)

Human

$299
Cat # M10524
50 µl

ROPN1 (NM_017578) Human Over-expression Lysate

Human

$628
Cat # LS054763
100 µg

ROPN1 Overview

Facts about Ropporin-1A.

ROPN1 3D structure. Source: alphafold

Ropporin-1A (ROPN1)

Significant for male fertility. With ROPN1L, involved in fibrous sheath ethics and sperm motility, plays a role in PKA- dependent signaling procedures needed for spermatozoa capacitation.

Gene Information

Human
Gene Name:	ROPN1
Uniprot:	Q9HAT0
Entrez:	54763

Family

Belongs to:

ropporin family

Alternative Names

Cancer/testis antigen 91; CT91Rhophilin-associated protein 1A; ODF6RHPNAP1; outer dense fiber of sperm tails 6; rhophilin associated tail protein 1; ROPN1ADKFZp434B1222; ropporin; ropporin, rhophilin associated protein 1; ropporin-1A

Molecular Weight

Mass (kDA):
23.893 kDA

Genomic Context


Human

Location:	3q21.1
Sequence:	3; NC_000003.12 (123968521..123992170, complement)

Tissue Specificity

Testis specific in adult. Overexpressed in hematologic tumor cells.

Subcellular Localizations

Cell projection, cilium, flagellum. In the sperm tail, found in the principal piece and in the cytoplasmic droplet located at the distal end of the midpiece. Inner surface of the fibrous sheath.

Diseases

Malignant Neoplasms
Hematologic Neoplasms
Leukemia, Myelocytic, Acute
Multiple Myeloma
Neoplasms
Myeloid Leukemia
Leukemia
Ischemic Stroke
Brain Ischemia
Male Infertility
Tissue Adhesions
Diabetes Mellitus

Infertility
Hypertensive Disease
Cardiovascular Diseases
Cerebrovascular Accident
Vascular Diseases
Lymphoid Leukemia
Chronic Lymphocytic Leukemia

Interacting Proteins

CKS1B
CNST
GNL3L
GPKOW
LENG1

LNX1
POLR3C
PRKAA1
PSMA1
RTP5

SDCBP
SPA17
TULP3
UBE2W
WDYHV1

Pathways

Acrosome Reaction
Localization
Spermatogenesis
Cell Adhesion
Sperm Motility
Translation
Sperm Capacitation

Pathogenesis
Cytokinesis

PTMs

Phosphorylation

Demethylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ROPN1

References

PMID: 17551920 by Li Z., et al. A yeast two-hybrid system using Sp17 identified ropporin as a novel cancer-testis antigen in hematologic malignancies.