Prokineticin receptor 1 Antibodies

AND PROKR1 ELISA kits, Prokineticin receptor 1 Proteins

Many biological assays use antibodies to detect Prokineticin receptor 1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Prokineticin receptor 1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Prokineticin receptor 1 antibodies...

We validate the specificity of these antibodies to Prokineticin receptor 1 by testing them on tissues known to express PROKR1 positively and negatively. Browse below to find the PROKR1 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PROKR1 Infographic by Boster Bio

All PROKR1 Products

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Anti-PKR1 PROKR1 Antibody

7 Q&As

Human, Mouse, Rat

$399
Cat # A10986
100μl

GPR73A (PROKR1) (NM_138964) Human Over-expression Lysate

Human

$628
Cat # LS010887
100 µg

PROKR1 Overview

Facts about Prokineticin receptor 1.

PROKR1 3D structure. Source: alphafold

Prokineticin receptor 1 (PROKR1)

Receptor for prokineticin 1. Exclusively coupled to the G(q) subclass of heteromeric G proteins.

Activation results in mobilization of calcium, stimulation of phosphoinositide turnover and activation of p44/p42 mitogen-activated protein kinase. May play a role during early pregnancy.

Gene Information

Human
Gene Name:	PROKR1
Uniprot:	Q8TCW9
Entrez:	10887

Family

Belongs to:

G-protein coupled receptor 1 family

Alternative Names

G protein-coupled receptor 73; G protein-coupled receptor ZAQ; GPR73; GPR73a; GPR73aG-protein coupled receptor 73; PKR1; PK-R1; PKR1G-protein coupled receptor ZAQ; Prokineticin R1; prokineticin receptor 1; ProkineticinR1; PROKR1; ZAQ

Molecular Weight

Mass (kDA):
44.77 kDA

Genomic Context


Human

Location:	2p13.3
Sequence:	2; NC_000002.12 (68643579..68658251)

Tissue Specificity

Localizes to glandular epithelium, stroma and vascular endothelial cells of first trimester decidua (at protein level). Up-regulated in first trimester decidua when compared with non-pregnant endometrium. Expressed in the stomach, throughout the small intestine, colon, rectum, thyroid gland, pituitary gland, salivary gland, adrenal gland, testis, ovary, brain, spleen, prostate and pancreas.

Subcellular Localizations

Cell membrane; Multi-pass membrane protein.

Diseases

Tumor Angiogenesis
Endometrial Polyp
Malignant Neoplasms
Pain
Mycoplasma Pneumonia
Hyperalgesia
Ectopic Pregnancy
Pre-eclampsia
Inflammatory Response
Tissue Adhesions
Fallopian Tube Diseases
Hypoxia
Prostatic Neoplasms

Fenestration (morphologic Abnormality)
Inflammation
Nervousness
Pancreatic Neoplasm
Hirschsprung Disease
Cell Invasion
Crest Syndrome

Pathways

Angiogenesis
Localization
Secretion
Inflammatory Response
Sensitization
Transport
Cell Adhesion
Monocyte Activation
Cell Proliferation
Circadian Rhythm
Parturition
Chemokine Production
Protein Maturation

Immune Response
Muscle Contraction
Neurogenesis
Spermatogenesis
Chemokine Secretion
Cell Differentiation
Epithelial Cell Proliferation

PTMs

Phosphorylation

Cleavage

Glycosylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PROKR1

References

PMID: 12054613 by Masuda Y., et al. Isolation and identification of EG-VEGF/prokineticins as cognate ligands for two orphan G-protein-coupled receptors.

PMID: 12427552 by Soga T., et al. Molecular cloning and characterization of prokineticin receptors.