Plexin-B1 Antibodies

AND PLXNB1 ELISA kits, Plexin-B1 Proteins

Many biological assays use antibodies to detect Plexin-B1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Plexin-B1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Plexin-B1 antibodies...

We validate the specificity of these antibodies to Plexin-B1 by testing them on tissues known to express PLXNB1 positively and negatively. Browse below to find the PLXNB1 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PLXNB1 Infographic by Boster Bio

All PLXNB1 Products

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Product

Figures

Specificity

Applications

Price

Anti-PLXB1 PLXNB1 Antibody

Human, Mouse

ELISA, WB

$380
Cat # A02711
100ul

Anti-PLXNB1 Antibody (C-term)

Human

$299
Cat # M02711
80 µl

Plexin B1 (PLXNB1) (NM_002673) Human Over-expression Lysate

Human

$960
Cat # LS005364
100 µg

PLXNB1 Overview

Facts about Plexin-B1.

PLXNB1 3D structure. Source: alphafold

Plexin-B1 (PLXNB1)

Receptor for SEMA4D.
Plays a role in RHOA activation and subsequent changes of the actin cytoskeleton.

Plays a role in axon guidance, invasive growth and cell migration. .

Gene Information

Human
Gene Name:	PLXNB1
Uniprot:	O43157
Entrez:	5364

Family

Belongs to:

plexin family

Alternative Names

Plexin B1; PLXN5; PLXNB1; SEP; Transmembrane Protein SEP

Molecular Weight

Mass (kDA):
232.298 kDA

Genomic Context


Human

Location:	3p21.31
Sequence:	3; NC_000003.12 (48403854..48430324, complement)

Tissue Specificity

Highly expressed in fetal kidney, and at slightly lower levels in fetal brain, lung and liver.

Subcellular Localizations

[Isoform 1]: Cell membrane; Single-pass type I membrane protein.; [Isoform 2]: Secreted.; [Isoform 3]: Secreted.

Diseases

Neoplasms
Nervousness
Malignant Neoplasms
Tumor Angiogenesis
Neoplasm Metastasis
Tissue Adhesions
Cell Invasion
Pathologic Neovascularization
Carcinoma
Tumor Progression
Neoplasm Invasiveness
Melanoma

Malignant Paraganglionic Neoplasm
Malignant Neoplasm Of Breast
Mammary Neoplasms
Endometrial Polyp
Cell Transformation, Neoplastic
Metastatic Malignant Neoplasm To The Lymph Node
Ovarian Neoplasm

Interacting Proteins

MET
MST1R
RND1
RND2
RND3

Pathways

Axon Guidance
Cell Migration
Angiogenesis
Cell Motility
Cell Adhesion
Localization
Secretion
Immune Response
Invasive Growth
Cell Proliferation
Endothelial Cell Migration
Pathogenesis
Cell Growth

Kidney Development
Cell Activation
Tube Formation
Neurogenesis
Platelet Activation
Steroid Hormone Secretion
Tropism

PTMs

Phosphorylation

Dephosphorylation

Cleavage

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PLXNB1

References

PMID: 10520995 by Tamagnone L., et al. Plexins are a large family of receptors for transmembrane, secreted and GPI-anchored semaphorins in vertebrates.

PMID: 8570614 by Maestrini E., et al. A family of transmembrane proteins with homology to the MET- hepatocyte growth factor receptor.