PLPP1 Antibodies

AND PLPP1 ELISA kits, PLPP1 Proteins

Many biological assays use antibodies to detect PLPP1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PLPP1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PLPP1 antibodies...

We validate the specificity of these antibodies to PLPP1 by testing them on tissues known to express PLPP1 positively and negatively. Browse below to find the PLPP1 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PLPP1 Infographic by Boster Bio

All PLPP1 Products

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Specificity

Applications

Price

Anti-PPAP2A (PLPP1) Mouse Monoclonal Antibody [Clone ID: OTI1H4]

Human

IHC, WB

$523
Cat # M11509
100 µl

PPAP2A (PLPP1) (NM_003711) Human Over-expression Lysate

Human

$628
Cat # LS008611
100 µg

PLPP1 Overview

Facts about Phospholipid phosphatase 1.

PLPP1 3D structure. Source: alphafold

Phospholipid phosphatase 1 (PLPP1)

Broad-specificity phosphohydrolase which dephosphorylates exogenous bioactive glycerolipids and sphingolipids. Pivotal regulator of lysophosphatidic acid (LPA) signaling in the cardiovascular system.

Major enzyme responsible of dephosphorylating LPA in platelets, which terminates signaling activities of LPA. May control circulating, and possibly also regulate localized, LPA levels caused by platelet activation.

Gene Information

Human
Gene Name:	PLPP1
Uniprot:	O14494
Entrez:	8611

Family

Belongs to:

PA-phosphatase related phosphoesterase family

Alternative Names

Phospholipid phosphatase 1

Molecular Weight

Mass (kDA):
32.156 kDA

Genomic Context


Human

Location:	5q11.2
Sequence:	5; NC_000005.10 (55424842..55535078, complement)

Tissue Specificity

Ubiquitously expressed with highest expression found in prostate. Isoform 1 is predominant in kidney, lung, placenta and liver. Isoform 2 is predominant in heart and pancreas. Found to be down-regulated in colon adenocarcinomas.

Subcellular Localizations

Cell membrane; Multi-pass membrane protein. Apical cell membrane; Multi-pass membrane protein. Membrane raft; Multi-pass membrane protein. Membrane, caveola; Multi-pass membrane protein.

PTMs

Glycoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PLPP1

References

PMID: 9305923 by Kai M., et al. Cloning and characterization of two human isozymes of Mg2+- independent phosphatidic acid phosphatase.

PMID: 9570154 by Leung D.W., et al. Molecular cloning of two alternatively spliced forms of human phosphatidic acid phosphatase cDNAs that are differentially expressed in normal and tumor cells.