Pyruvate kinase PKM Antibodies

AND PKM ELISA kits, Pyruvate kinase PKM Proteins

Many biological assays use antibodies to detect Pyruvate kinase PKM, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Pyruvate kinase PKM in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Pyruvate kinase PKM antibodies...

We validate the specificity of these antibodies to Pyruvate kinase PKM by testing them on tissues known to express PKM positively and negatively. Browse below to find the PKM antibody that suites your experiment. We have 8 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PKM Infographic by Boster Bio

All PKM Products

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Product

Figures

Specificity

Applications

Price

Anti-PKM2 Antibody Picoband®

1 Q&As

Human, Mouse, Rat

IF, IHC, ICC, WB

$370
Cat # PB9379
100 μg/vial

Anti-PKM2 Antibody Picoband®

5 Q&As

Human

$370
Cat # PA2046
100 μg/vial

Anti-PKM2 Rabbit Monoclonal Antibody

1 Citations

Human, Mouse, Rat

Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # M01173
100 μl

Anti-PKM2 Antibody

Human, Mouse, Rat

IP, IF, IHC, WB, RIP

$405
Cat # A01173-1
100ul

Human PKM2 Recombinant Protein

Enzyme Activity, SDS-PAGE

$243
Cat # PROTP14618
Starting from 20ug

Mouse Pkm Recombinant Protein

Enzyme Activity, SDS-PAGE

$218
Cat # PROTP52480
Starting from 4ug

Anti-PKM2 Antibody Picoband® (monoclonal, 11I4C3)

Human

Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # M01173-1
100 μg/vial

PKM2 (PKM) (NM_002654) Human Over-expression Lysate

Human

$628
Cat # LS005315
100 µg

PKM Overview

Facts about Pyruvate kinase PKM.

PKM 3D structure. Source: alphafold

Pyruvate kinase PKM (PKM)

Glycolytic enzyme that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate (PEP) to ADP, generating ATP. Stimulates POU5F1-mediated transcriptional activation.

Plays a general role in caspase independent cell death of tumor cells. The ratio between the highly active tetrameric form and nearly inactive dimeric form determines whether glucose carbons are channeled to biosynthetic processes or used for glycolytic ATP production.

Gene Information

Human
Gene Name:	PKM
Uniprot:	P14618
Entrez:	5315

Family

Belongs to:

pyruvate kinase family

Alternative Names

CTHBP; Cytosolic thyroid hormone-binding protein; MGC3932; OIP3; OIP-3; OIP3EC 2.7.1.40; Opa-interacting protein 3; p58; PK, muscle type; PK2; PK3; PK3PKM; PKM2; Pyruvate kinase 2/3; pyruvate kinase isozymes M1/M2; Pyruvate kinase muscle isozyme; pyruvate kinase, muscle; TCB; THBP1; THBP1p58; Thyroid hormone-binding protein 1; thyroid hormone-binding protein, cytosolic; Tumor M2-PK

Molecular Weight

Mass (kDA):
57.937 kDA

Genomic Context


Human

Location:	15q23
Sequence:	15; NC_000015.10 (72199029..72231624, complement)

Tissue Specificity

Specifically expressed in proliferating cells, such as embryonic stem cells, embryonic carcinoma cells, as well as cancer cells.

Subcellular Localizations

Cytoplasm. Nucleus. Translocates to the nucleus in response to different apoptotic stimuli. Nuclear translocation is sufficient to induce cell death that is caspase independent, isoform-specific and independent of its enzymatic activity.