PIGR Antibodies

AND PIGR ELISA kits, PIGR Proteins

Many biological assays use antibodies to detect PIGR, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PIGR in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PIGR antibodies...

We validate the specificity of these antibodies to PIGR by testing them on tissues known to express PIGR positively and negatively. Browse below to find the PIGR antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PIGR Infographic by Boster Bio

All PIGR Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-PIGR Antibody Picoband®

6 Q&As

Human

$370
Cat # PB9776
100 μg/vial

Anti-Polymeric immunoglobulin receptor/PIGR Picoband® Antibody

Mouse, Rat

ELISA, Flow Cytometry, WB

$370
Cat # A01624
100 μg/vial

PIGR (NM_002644) Human Recombinant Protein

$1062
Cat # PROTP01833
20 µg

Human PIGR ELISA Kit PicoKine®

Human

ELISA

$499
Cat # EK2261
96 wells/kit, with removable strips.

PIGR Overview

Facts about Polymeric immunoglobulin receptor.

PIGR 3D structure. Source: alphafold

Polymeric immunoglobulin receptor (PIGR)

This receptor binds polymeric IgA and IgM in the basolateral surface of epithelial cells. The complex is then transported across the cell to be secreted in the apical surface.

During this process a cleavage occurs that divides the extracellular (known as the secretory component) in the transmembrane segment. .

Gene Information

Human
Gene Name:	PIGR
Uniprot:	P01833
Entrez:	5284

Family

Belongs to:

No superfamily

Alternative Names

FLJ22667; Free Secretory Component (FSC) ; hepatocellular carcinoma associated protein TB6; Hepatocellular carcinoma-associated protein TB6; MGC125361; MGC125362; pIgA-Secretory Component Complex; pIgM-Secretory Component Complex; pIgR; Poly-Ig receptor; polymeric immunoglobulin receptor; Secretory Component (SC); sIgA-Secretory Component Complex

Molecular Weight

Mass (kDA):
83.284 kDA

Genomic Context


Human

Location:	1q32.1
Sequence:	1; NC_000001.11 (206928522..206946466, complement)

Subcellular Localizations

Cell membrane; Single-pass type I membrane protein.; [Secretory component]: Secreted.

Diseases

Malignant Neoplasms
Carcinoma
Colorectal Cancer
Adenoma
Malignant Tumor Of Colon
Neoplasms
Impacted Tooth
Colorectal Neoplasms
Inflammation
Malignant Squamous Cell Neoplasm
Cattle Diseases
Stomach Neoplasms

Inflammatory Bowel Diseases
Lung Diseases
Neoplasm Invasiveness
Intestinal Diseases
Lung Diseases, Obstructive
Dysplasia
Fibrosis

Pathways

Transport
Localization
Transcytosis
Pathogenesis
Chromosome Localization
Complement Activation
Hypersensitivity
Metaphase
Disease Resistance
Transepithelial Transport

Regeneration
Translation
Liver Regeneration
Fatty Acid Oxidation
Secretion

PTMs

Glycosylation

Acetylation

Oxidation

Research Areas

Immunology

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PIGR

References

PMID: 1682231 by Krajci P., et al. The human transmembrane secretory component (poly-Ig receptor): molecular cloning, restriction fragment length polymorphism and chromosomal sublocalization.

PMID: 1355431 by Krajci P., et al. Molecular cloning and exon-intron mapping of the gene encoding human transmembrane secretory component (the poly-Ig receptor).