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- Table of Contents
Facts about PHD finger protein 12.
Represses transcription at least in part through the action of an associated histone deacetylase (HDAC). May also repress transcription in a SIN3A-independent way through recruitment of functional AES complexes to DNA.
Human | |
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Gene Name: | PHF12 |
Uniprot: | Q96QT6 |
Entrez: | 57649 |
Belongs to: |
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No superfamily |
FLJ34122; KIAA1523MGC131914; PF1; PHD factor 1; PHD finger protein 12; PHD zinc finger transcription factor
Mass (kDA):
109.698 kDA
Human | |
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Location: | 17q11.2 |
Sequence: | 17; NC_000017.11 (28905250..28951518, complement) |
Nucleus.
PMID: 11390640 by Yochum G.S., et al. Pf1, a novel PHD zinc finger protein that links the TLE corepressor to the mSin3A-histone deacetylase complex.
PMID: 16893883 by Kaadige M.R., et al. The polybasic region that follows the plant homeodomain zinc finger 1 of Pf1 is necessary and sufficient for specific phosphoinositide binding.