PDCD10 Antibodies

AND PDCD10 ELISA kits, PDCD10 Proteins

Many biological assays use antibodies to detect PDCD10, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PDCD10 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PDCD10 antibodies...

We validate the specificity of these antibodies to PDCD10 by testing them on tissues known to express PDCD10 positively and negatively. Browse below to find the PDCD10 antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PDCD10 Infographic by Boster Bio

All PDCD10 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-PDCD10 Antibody Picoband®

Human, Mouse, Rat

ELISA, WB

$370
Cat # A01879-1
100 μg/vial

Anti-Human PDCD10 DyLight® 488 conjugated Antibody

1 Q&As

Human

Flow Cytometry

$515
Cat # A01879-Dyl488
100 μg/vial

Anti-Human PDCD10 DyLight® 550 conjugated Antibody

7 Q&As

Human

Flow Cytometry

$515
Cat # A01879-Dyl550
100 μg/vial

PDCD10 (NM_007217) Human Recombinant Protein

$1062
Cat # PROTQ9BUL8
20 µg

PDCD10 (NM_007217) Human Over-expression Lysate

Human

$628
Cat # LS011235
100 µg

PDCD10 Overview

Facts about Programmed cell death protein 10.

PDCD10 3D structure. Source: alphafold

Programmed cell death protein 10 (PDCD10)

Promotes cell proliferation. Modulates apoptotic pathways.

Increases mitogen-activated protein kinase activity and STK26 activity (PubMed:27807006). Important for cell migration, and for regular structure and assembly of the Golgi complex (PubMed:27807006).

Gene Information

Human
Gene Name:	PDCD10
Uniprot:	Q9BUL8
Entrez:	11235

Family

Belongs to:

PDCD10 family

Alternative Names

apoptosis-related protein 15; cerebral cavernous malformations 3; MGC1212; MGC24477; programmed cell death 10; programmed cell death protein 10; TF-1 cell apoptosis-related protein 15; TFAR15CCM3Cerebral cavernous malformations 3 protein

Molecular Weight

Mass (kDA):
24.702 kDA

Genomic Context


Human

Location:	3q26.1
Sequence:	3; NC_000003.12 (167683298..167735810, complement)

Tissue Specificity

Ubiquitous.

Subcellular Localizations

Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Partially co-localizes with endogenous PXN at the leading edges of migrating cells.

Diseases

Cavernous Hemangioma Of Brain
Hemangioma, Cavernous, Central Nervous System
Cerebrovascular Accident
Nervousness
Vascular Anomaly
Headache
Hemorrhage
Brain Hemorrhage
Brain Neoplasms
Congenital Vascular Anomaly
Tumor Angiogenesis
Malignant Neoplasms

Neoplasms
Central Nervous System Neoplasms
Intracranial Arteriovenous Malformation
Central Nervous System Vascular Malformations
Hemangioma, Cavernous
Pathologic Neovascularization
Epilepsy

Interacting Proteins

C4orf19
CCM2
PTPN13
STK24
STK25

STK26
STRN

Pathways

Cell Death
Pathogenesis
Programmed Cell Death
Angiogenesis
Cell Proliferation
Localization
Tube Formation
Vasculogenesis
Cell Cycle
Cell Migration
Hyperphosphorylation
Golgi Localization
Gene Silencing

Fertilization
Brain Development
Golgi Disassembly
Endothelial Cell Proliferation
Spermatogenesis
Cell Cycle Arrest
Response To Oxidative Stress

PTMs

Phosphorylation

Dephosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PDCD10

References

PMID: 15543491 by Bergametti F., et al. Mutations within the programmed cell death 10 gene cause cerebral cavernous malformations.

PMID: 17360971 by Ma X., et al. PDCD10 interacts with Ste20-related kinase MST4 to promote cell growth and transformation via modulation of the ERK pathway.