PAGR1 Antibodies

AND PAGR1 ELISA kits, PAGR1 Proteins

Many biological assays use antibodies to detect PAGR1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PAGR1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PAGR1 antibodies...

We validate the specificity of these antibodies to PAGR1 by testing them on tissues known to express PAGR1 positively and negatively. Browse below to find the PAGR1 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PAGR1 Infographic by Boster Bio

All PAGR1 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-GAS PAGR1 Antibody

Human, Mouse

ELISA, WB

$449
Cat # A13756
0.1 mg

PA1 (PAGR1) (NM_024516) Human Recombinant Protein

$813
Cat # PROTQ9BTK6
20 µg

PA1 (PAGR1) (NM_024516) Human Over-expression Lysate

Human

$628
Cat # LS079447
100 µg

PAGR1 Overview

Facts about PAXIP1-associated glutamate-rich protein 1.

PAGR1 3D structure. Source: alphafold

PAXIP1-associated glutamate-rich protein 1 (PAGR1)

Its association with the histone methyltransferase MLL2/MLL3 complex is indicating a role in epigenetic transcriptional activation. Nevertheless, in affiliation with PAXIP1/PTIP is suggested to function at least in part independently of the MLL2/MLL3 complex.

Proposed to be recruited by PAXIP1 to sites of DNA damage where the PAGR1:PAXIP1 complex is necessary for cell survival in response to DNA damage independently of the MLL2/MLL3 complex (PubMed:19124460). However, its role in DNA damage was contested (By similarity).

Gene Information

Human
Gene Name:	PAGR1
Uniprot:	Q9BTK6
Entrez:	79447

Family

Belongs to:

No superfamily

Alternative Names

chromosome 16 open reading frame 53; FLJ22459; GAS; glutamate-rich coactivator interacting with SRC1/NCOA1; MGC4606; PA1; PAXIP1-associated protein 1; PTIP-associated 1 protein; PTIP-associated protein 1

Molecular Weight

Mass (kDA):
27.716 kDA

Genomic Context


Human

Location:	16p11.2
Sequence:	16; NC_000016.10 (29816152..29822489)

Tissue Specificity

Ubiquitously expressed.

Subcellular Localizations

Nucleus.

Interacting Proteins

ESR1
NCOA1
Nr3c1
PAXIP1
Paxip1

PTMs

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PAGR1

References

PMID: 17500065 by Cho Y.-W., et al. PTIP associates with MLL3- and MLL4-containing histone H3 lysine 4 methyltransferase complex.

PMID: 19039327 by Liang J., et al. GAS, a new glutamate-rich protein, interacts differentially with SRCs and is involved in oestrogen receptor function.