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- Table of Contents
Facts about Protein NDNF.
Promotes endothelial cell survival, vessel formation and plays an significant role in the process of revascularization via NOS3-dependent mechanics (PubMed:24706764). .
Mouse | |
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Gene Name: | Ndnf |
Uniprot: | Q8C119 |
Entrez: | 68169 |
Belongs to: |
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No superfamily |
Protein NDNF
Mass (kDA):
65.027 kDA
Mouse | |
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Location: | 6|6 C1 |
Sequence: | 6; |
Expressed in brain and spinal cord with no expression detected in heart, kidney or liver. Expressed by neurons but not by astrocytes. In the brain, detected in the cerebrum, cerebellum and olfactory bulbs. In the cerebral cortex, highly expressed in Cajal-Retzius cells. Also expressed in hippocampal neurons and in Purkinje and granule cells of the cerebellum (at protein level).
PMID: 18757743 by Manabe R., et al. Transcriptome-based systematic identification of extracellular matrix proteins.
PMID: 20969804 by Kuang X.L., et al. Spatio-temporal expression of a novel neuron-derived neurotrophic factor (NDNF) in mouse brains during development.