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- Table of Contents
Facts about Moesin.
Plays a role in regulating the proliferation, migration, and adhesion of human lymphoid cells and participates in immunologic synapse formation (PubMed:27405666). .
Human | |
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Gene Name: | MSN |
Uniprot: | P26038 |
Entrez: | 4478 |
Belongs to: |
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No superfamily |
Membrane-organizing extension spike protein; moesin
Mass (kDA):
67.82 kDA
Human | |
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Location: | Xq12 |
Sequence: | X; NC_000023.11 (65588382..65741931) |
In all tissues and cultured cells studied.
Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton. Apical cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection, microvillus membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection, microvillus. Phosphorylated form is enriched in microvilli-like structures at apical membrane. Increased cell membrane localization of both phosphorylated and non-phosphorylated forms seen after thrombin treatment (By similarity). Localizes at the uropods of T lymphoblasts.
PMID: 1924289 by Lankes W.T., et al. Moesin: a member of the protein 4.1-talin-ezrin family of proteins.
PMID: 7884872 by Schneider-Schaulies J., et al. Physical association of moesin and CD46 as a receptor complex for measles virus.