Protein Mis18-alpha Antibodies

AND MIS18A ELISA kits, Protein Mis18-alpha Proteins

Many biological assays use antibodies to detect Protein Mis18-alpha, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Protein Mis18-alpha in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Protein Mis18-alpha antibodies...

We validate the specificity of these antibodies to Protein Mis18-alpha by testing them on tissues known to express MIS18A positively and negatively. Browse below to find the MIS18A antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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MIS18A Infographic by Boster Bio

All MIS18A Products

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C21orf45 (MIS18A) (NM_018944) Human Over-expression Lysate

Human

$628
Cat # LS054069
100 µg

Anti-C21orf45/MIS18A Antibody Picoband®

Human

ELISA, Flow Cytometry, IF, ICC, WB

$370
Cat # A10791-1
100 µg/vial

MIS18A Overview

Facts about Protein Mis18-alpha.

MIS18A 3D structure. Source: alphafold

Protein Mis18-alpha (MIS18A)

Required for recruitment of CENPA to centromeres and normal chromosome segregation during mitosis. .

Gene Information

Human
Gene Name:	MIS18A
Uniprot:	Q9NYP9
Entrez:	54069

Family

Belongs to:

mis18 family

Alternative Names

B28; C21orf45; C21orf46; FAPP1-associated protein 1; FASP1; hMis18alpha; MIS18 kinetochore protein homolog A (S. pombe); MIS18alpha; protein Mis18-alpha

Molecular Weight

Mass (kDA):
25.863 kDA

Genomic Context


Human

Location:	21q22.11
Sequence:	21; NC_000021.9 (32154682..32283954, complement)

Tissue Specificity

Detected in testis.

Subcellular Localizations

Nucleus. Chromosome. Chromosome, centromere. Associated with centromeres in interphase cells, from late anaphase to the G1 phase. Not detected on centromeres during earlier phases of mitosis. Associated with chromatin.

Interacting Proteins

AIMP2
ANKRD36BP1
NDEL1
OIP5
TXLNA

Pathways

Mitosis
Telophase
Interphase
Localization
Anaphase

PTMs

Acetylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MIS18A

References

PMID: 10773462 by Slavov D., et al. Criteria for gene identification and features of genome organization: analysis of 6.5 Mb of DNA sequence from human chromosome 21.

PMID: 17199038 by Fujita Y., et al. Priming of centromere for CENP-A recruitment by human hMis18alpha, hMis18beta, and M18BP1.