Homeobox protein Meis1 Antibodies

AND MEIS1 ELISA kits, Homeobox protein Meis1 Proteins

Many biological assays use antibodies to detect Homeobox protein Meis1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Homeobox protein Meis1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Homeobox protein Meis1 antibodies...

We validate the specificity of these antibodies to Homeobox protein Meis1 by testing them on tissues known to express MEIS1 positively and negatively. Browse below to find the MEIS1 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Previous: CBLIF Next: MEIS2

MEIS1 Infographic by Boster Bio

All MEIS1 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-MEIS1 Monoclonal Antibody

7 Q&As

Human, Mouse, Rat

Flow Cytometry, IP, WB

$370
Cat # M01602
100 μl

Anti-Homeobox protein Meis1 MEIS1 Antibody

Human, Mouse, Rat

Flow Cytometry, IP, WB

$405
Cat # A01602-1
100ul

Anti-MEIS1 Mouse Monoclonal Antibody [Clone ID: OTI2A3]

+12

Human

IHC, WB

$523
Cat # M01602-1
100 µl

MEIS1 Overview

Facts about Homeobox protein Meis1.

MEIS1 3D structure. Source: alphafold

Homeobox protein Meis1 (MEIS1)

Acts as a transcriptional regulator of PAX6.
Acts as a transcriptional activator of PF4 in complex with PBX1 or PBX2.

Required for hematopoiesis, megakaryocyte lineage development and vascular patterning. May serve as a cofactor for HOXA7 and HOXA9 in the induction of myeloid leukemias.

Gene Information

Human
Gene Name:	MEIS1
Uniprot:	O00470
Entrez:	4211

Family

Belongs to:

TALE/MEIS homeobox family

Alternative Names

homeobox protein Meis1; leukemogenic homolog protein; Meis homeobox 1; MGC43380; myeloid ecotropic viral integration site 1 homolog (mouse); myeloid ecotropic viral integration site 1 homolog

Molecular Weight

Mass (kDA):
43.016 kDA

Genomic Context


Human

Location:	2p14
Sequence:	2; NC_000002.12 (66435125..66573869)

Tissue Specificity

Expressed at low level in normal immunohepatopoietic tissues, including the fetal liver. Expressed in a subset of myeloid leukemia cell lines, with the highest expression seen in those with a megakaryocytic-erythroid phenotype. Also expressed at high levels in the cerebellum.

Subcellular Localizations

Nucleus.

Diseases

Leukemia
Myeloid Leukemia
Leukemia, Myelocytic, Acute
Leukemogenesis
Cell Transformation, Neoplastic
Malignant Neoplasms
Neoplasms
Chromosomal Translocation
Agitation
Restless Legs Syndrome
Acute Lymphocytic Leukemia
Malignant Paraganglionic Neoplasm
Acute Leukemia

Neuroblastoma
Nervousness
Carcinoma
Precursor B-cell Lymphoblastic Leukemia-lymphoma
Myeloid Leukemia, Chronic
Tumor Angiogenesis
Embryonal Carcinoma

Interacting Proteins

CREB1
ETS1
TLX1

Pathways

Localization
Methylation
Pathogenesis
Cell Differentiation
Cell Proliferation
Cell Cycle
Limb Development
Eye Development
Cell Growth
Angiogenesis
Histone Acetylation
Oncogenesis
Dna Methylation

Dna Hypermethylation
Neurogenesis
Reverse Transcription
Rna Interference
Cell Maturation
Antennal Development
Stem Cell Differentiation

PTMs

Methylation
Acetylation
Phosphorylation

Ubiquitination
Reduction
Deacetylation

Cleavage

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MEIS1

References

PMID: 9226379 by Smith J.E. Jr., et al. Cloning and mapping of the MEIS1 gene, the human homolog of a murine leukemogenic gene.

PMID: 12609849 by Okada Y., et al. Homeodomain proteins MEIS1 and PBXs regulate the lineage-specific transcription of the platelet factor 4 gene.