MARCHF9 Antibodies

AND MARCHF9 ELISA kits, MARCHF9 Proteins

Many biological assays use antibodies to detect MARCHF9, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with MARCHF9 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop MARCHF9 antibodies...

We validate the specificity of these antibodies to MARCHF9 by testing them on tissues known to express MARCHF9 positively and negatively. Browse below to find the MARCHF9 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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MARCHF9 Infographic by Boster Bio

All MARCHF9 Products

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MARCHF9 (NM_138396) Human Over-expression Lysate

Human

$628
Cat # LS092979
100 µg

MARCHF9 Overview

Facts about E3 ubiquitin-protein ligase MARCHF9.

MARCHF9 3D structure. Source: alphafold

E3 ubiquitin-protein ligase MARCHF9 (MARCHF9)

E3 ubiquitin-protein ligase that may mediate ubiquitination of MHC-I, CD4 and ICAM1, and promote their subsequent endocytosis and sorting to lysosomes through multivesicular bodies. E3 ubiquitin ligases take ubiquitin from an E2 ubiquitin-conjugating enzyme in the shape of a thioester and then directly transfer the ubiquitin to targeted substrates.

Gene Information

Human
Gene Name:	MARCHF9
Uniprot:	Q86YJ5
Entrez:	92979

Family

Belongs to:

No superfamily

Alternative Names

E3 ubiquitin-protein ligase MARCHF9

Molecular Weight

Mass (kDA):
37.772 kDA

Genomic Context


Human

Location:	12q14.1
Sequence:	12; NC_000012.12 (57755103..57760411)

Tissue Specificity

Ubiquitously expressed.

Subcellular Localizations

Golgi apparatus membrane; Multi-pass membrane protein. Lysosome membrane; Multi-pass membrane protein.

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MARCHF9

References

PMID: 14722266 by Bartee E., et al. Downregulation of major histocompatibility complex class I by human ubiquitin ligases related to viral immune evasion proteins.

PMID: 17174307 by Hoer S., et al. MARCH-IX mediates ubiquitination and downregulation of ICAM-1.