MARCHF4 Antibodies

AND MARCHF4 ELISA kits, MARCHF4 Proteins

Many biological assays use antibodies to detect MARCHF4, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with MARCHF4 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop MARCHF4 antibodies...

We validate the specificity of these antibodies to MARCHF4 by testing them on tissues known to express MARCHF4 positively and negatively. Browse below to find the MARCHF4 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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MARCHF4 Infographic by Boster Bio

All MARCHF4 Products

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MARCHF4 (NM_020814) Human Over-expression Lysate

Human

$628
Cat # LS057574
100 µg

MARCHF4 Overview

Facts about E3 ubiquitin-protein ligase MARCHF4.

MARCHF4 3D structure. Source: alphafold

E3 ubiquitin-protein ligase MARCHF4 (MARCHF4)

E3 ubiquitin-protein ligase that may mediate ubiquitination of MHC-I and CD4, and promote their subsequent endocytosis and sorting to lysosomes through multivesicular bodies. E3 ubiquitin ligases take ubiquitin from an E2 ubiquitin- conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.

Gene Information

Human
Gene Name:	MARCHF4
Uniprot:	Q9P2E8
Entrez:	57574

Family

Belongs to:

No superfamily

Alternative Names

E3 ubiquitin-protein ligase MARCHF4

Molecular Weight

Mass (kDA):
45.528 kDA

Genomic Context


Human

Location:	2q35
Sequence:	2; NC_000002.12 (216257865..216372483, complement)

Tissue Specificity

Expressed in brain and placenta.

Subcellular Localizations

Golgi apparatus membrane; Multi-pass membrane protein.

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MARCHF4

References

PMID: 14722266 by Bartee E., et al. Downregulation of major histocompatibility complex class I by human ubiquitin ligases related to viral immune evasion proteins.