MARCHF2 Antibodies

AND MARCHF2 ELISA kits, MARCHF2 Proteins

Many biological assays use antibodies to detect MARCHF2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with MARCHF2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop MARCHF2 antibodies...

We validate the specificity of these antibodies to MARCHF2 by testing them on tissues known to express MARCHF2 positively and negatively. Browse below to find the MARCHF2 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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MARCHF2 Infographic by Boster Bio

All MARCHF2 Products

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Product

Figures

Specificity

Applications

Price

MARCHF2 (NM_016496) Human Over-expression Lysate

Human

$628
Cat # LS051257
100 µg

Anti-MARCHF2 Antibody Picoband®

Human

ELISA, IF, ICC, WB

$370
Cat # A13497-2
100 µg/vial

MARCHF2 Overview

Facts about E3 ubiquitin-protein ligase MARCHF2.

MARCHF2 3D structure. Source: alphafold

E3 ubiquitin-protein ligase MARCHF2 (MARCHF2)

E3 ubiquitin-protein ligase that may mediate ubiquitination of TFRC and CD86, and promote their subsequent endocytosis and sorting to lysosomes through multivesicular bodies. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin- conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.

May be involved in endosomal trafficking through interaction with STX6. .

Gene Information

Human
Gene Name:	MARCHF2
Uniprot:	Q9P0N8
Entrez:	51257

Family

Belongs to:

No superfamily

Alternative Names

E3 ubiquitin-protein ligase MARCHF2

Molecular Weight

Mass (kDA):
26.995 kDA

Genomic Context


Human

Location:	19p13.2
Sequence:	19; NC_000019.10 (8413303..8439017)

Tissue Specificity

Broadly expressed.

Subcellular Localizations

Endoplasmic reticulum membrane; Multi-pass membrane protein. Lysosome membrane; Multi-pass membrane protein. Endosome membrane; Multi-pass membrane protein.

Interacting Proteins

CCDC155
FATE1
LDLRAD1
SYNE4

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/MARCHF2

References

PMID: 15689499 by Nakamura N., et al. MARCH-II is a syntaxin-6-binding protein involved in endosomal trafficking.

PMID: 14722266 by Bartee E., et al. Downregulation of major histocompatibility complex class I by human ubiquitin ligases related to viral immune evasion proteins.