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- Table of Contents
Facts about Lymphocyte antigen 6H.
May play a role in the intracellular trafficking of alpha-7-containing nAChRs and might inhibit their expression at the cell surface. Seems to inhibit alpha-7/CHRNA7 signaling in hippocampal neurons.
Human | |
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Gene Name: | LY6H |
Uniprot: | O94772 |
Entrez: | 4062 |
Belongs to: |
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No superfamily |
ly-6H; lymphocyte antigen 6 complex, locus H; lymphocyte antigen 6H; NMLY6
Mass (kDA):
14.669 kDA
Human | |
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Location: | 8q24.3 |
Sequence: | 8; NC_000008.11 (143157916..143160654, complement) |
Highly expressed in brain (cerebral cortex, amygdala, hippocampus and subthalamic nucleus) and in acute human leukemic cell line MOLT-3. Also found in lower levels in testis, pancreas, small intestine and colon.
Cell membrane; Lipid-anchor, GPI-anchor.
PMID: 9799603 by Horie M., et al. Isolation and characterization of a new member of the human Ly6 gene family (LY6H).