Lymphocyte antigen 6H (LY6H)

Believed to serve as a modulator of nicotinic acetylcholine receptors (nAChRs) activity. In vitro inhibits alpha-3:beta-4-containing nAChRs maximum reaction.

May play a role in the intracellular trafficking of alpha-7-containing nAChRs and might inhibit their expression at the cell surface. Seems to inhibit alpha-7/CHRNA7 signaling in hippocampal neurons.