Lclat1 Antibodies

AND Lclat1 ELISA kits, Lclat1 Proteins

Many biological assays use antibodies to detect Lclat1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Lclat1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Lclat1 antibodies...

We validate the specificity of these antibodies to Lclat1 by testing them on tissues known to express Lclat1 positively and negatively. Browse below to find the Lclat1 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Previous: Septin9 Next: Fez2

Lclat1 Infographic by Boster Bio

All Lclat1 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

LCLAT1 (NM_182551) Human Over-expression Lysate

Human

$628
Cat # LS253558
100 µg

Lclat1 Overview

Facts about Lysocardiolipin acyltransferase 1.

Lysocardiolipin acyltransferase 1 (Lclat1)

Acyl-CoA:lysocardiolipin acyltransferase. Possesses both lysophosphatidylinositol acyltransferase (LPIAT) and lysophosphatidylglycerol acyltransferase (LPGAT) activities.

Recognizes both monolysocardiolipin and dilysocardiolipin as substrates with a preference for linoleoyl-CoA and oleoyl-CoA as acyl donors. Acts as a remodeling enzyme for cardiolipin, a significant membrane polyglycerophospholipid.

Gene Information

Mouse
Gene Name:	Lclat1
Uniprot:	Q3UN02
Entrez:	225010

Family

Belongs to:

1-acyl-sn-glycerol-3-phosphate acyltransferase family

Alternative Names

1-acylglycerol-3-phosphate O-acyltransferase 8; 1-AGPAT 8; Acyl-CoA:lysocardiolipin acyltransferase 1; AGPAT8lysocardiolipin acyltransferase; ALCAT11AGPAT8; EC 2.3.1.-; EC 2.3.1.51; FLJ37965; HSRG1849; LYCAT; lysocardiolipin acyltransferase 1; UNQ1849,1-AGP acyltransferase 8

Molecular Weight

Mass (kDA):
44.4 kDA

Genomic Context


Mouse

Location:	17\|17 E1.3-E2
Sequence:	17;

Tissue Specificity

Widely expressed with highest expression in heart, liver and E12.5 aorta-gonad-mesonephros and lower levels in the E16 fetal liver and adult bone marrow. In bone marrow, highest levels are found in B-cells compared with whole bone marrow, T- cells, erythrocytes, and granulocytes.

PTMs

Acetylation

Glycoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Lclat1

References

PMID: 15152008 by Cao J., et al. A novel cardiolipin-remodeling pathway revealed by a gene encoding an endoplasmic reticulum-associated acyl-CoA:lysocardiolipin acyltransferase (ALCAT1) in mouse.

PMID: 16620771 by Agarwal A.K., et al. Functional characterization of human 1-acylglycerol-3-phosphate acyltransferase isoform 8: cloning, tissue distribution, gene structure, and enzymatic activity.