KMT5C Antibodies

AND KMT5C ELISA kits, KMT5C Proteins

Many biological assays use antibodies to detect KMT5C, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with KMT5C in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop KMT5C antibodies...

We validate the specificity of these antibodies to KMT5C by testing them on tissues known to express KMT5C positively and negatively. Browse below to find the KMT5C antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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KMT5C Infographic by Boster Bio

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KMT5C (NM_032701) Human Over-expression Lysate

Human

$628
Cat # LS084787
100 µg

KMT5C Overview

Facts about Histone-lysine N-methyltransferase KMT5C.

KMT5C 3D structure. Source: alphafold

Histone-lysine N-methyltransferase KMT5C (KMT5C)

Histone methyltransferase that specifically trimethylates'Lys-20' of histone H4. H4 'Lys-20' trimethylation represents a specific tag for epigenetic transcriptional repression.

Mainly functions in pericentric heterochromatin regions, thereby playing a central role in the organization of constitutive heterochromatin in these regions. KMT5C is targeted to histone H3 via its interaction with RB1 family proteins (RB1, RBL1 and RBL2) (By similarity).

Gene Information

Human
Gene Name:	KMT5C
Uniprot:	Q86Y97
Entrez:	84787

Family

Belongs to:

class V-like SAM-binding methyltransferase superfamily

Alternative Names

Histone-lysine N-methyltransferase KMT5C

Molecular Weight

Mass (kDA):
52.113 kDA

Genomic Context


Human

Location:	19q13.42
Sequence:	19; NC_000019.10 (55339876..55348121)

Subcellular Localizations

Nucleus. Chromosome. Associated with pericentric heterochromatin. CBX1 and CBX5 are required for the localization to pericentric heterochromatin (By similarity).

Interacting Proteins

CBX3

PTMs

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/KMT5C

References

PMID: 15057824 by Grimwood J., et al. The DNA sequence and biology of human chromosome 19.

PMID: 15498874 by Wan D., et al. Large-scale cDNA transfection screening for genes related to cancer development and progression.