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Integrin alpha-4 Antibodies
AND ITGA4 ELISA kits, Integrin alpha-4 Proteins
Many biological assays use antibodies to detect Integrin alpha-4, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Integrin alpha-4 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Integrin alpha-4 antibodies...
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ITGA4 Infographic by Boster Bio
All ITGA4 Products
Product
Figures
Specificity
Applications
Price
Human, Rat
Flow Cytometry, IHC, IHC-F, WB
$370
Cat # PB9648
100 μg/vial
Cat # PB9648
100 μg/vial
Human
IHC, WB
$431
Cat # M00468-1
100uL
Cat # M00468-1
100uL
Human, Mouse
ELISA, IF, IHC
$380
Cat # A00468S1027
100ul
Cat # A00468S1027
100ul
Mouse, Rat
ELISA, Flow Cytometry, WB
$370
Cat # A00468-2
100 µg/vial
Cat # A00468-2
100 µg/vial
Human
ELISA, Flow Cytometry, FTA
$349
Cat # M00468-2
100 μg
Cat # M00468-2
100 μg
ITGA4 Overview
Facts about Integrin alpha-4.
Integrin alpha-4 (ITGA4)
They recognize one or more domain names within the alternatively spliced CS-1 and CS-5 regions of fibronectin. They are also receptors for VCAM1.
Integrin alpha- 4/beta-1 recognizes the sequence Q-I-D-S in VCAM1. Integrin alpha- 4/beta-7 is also a receptor for MADCAM1.
Gene Information
| Human | |
|---|---|
| Gene Name: | ITGA4 |
| Uniprot: | P13612 |
| Entrez: | 3676 |
Family
| Belongs to: |
|---|
| integrin alpha chain family |
Alternative Names
269C wild type; CD49 antigen-like family member D; CD49d antigen; CD49d; CD49Dantigen CD49D, alpha-4 subunit of VLA-4 receptor; IA4; Integrin alpha 4; integrin alpha-4 subunit; integrin alpha-4; Integrin alpha-IV; integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor); ITGA4; MGC90518; very late activation protein 4 receptor, alpha 4 subunit; VLA-4 subunit alpha; VLA-4
Molecular Weight
Mass (kDA):
114.9 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 2q31.3 |
| Sequence: | 2; NC_000002.12 (181456892..181538940) |
Subcellular Localizations
Membrane; Single-pass type I membrane protein.
Diseases
- Tissue Adhesions
- Neoplasms
- Malignant Neoplasms
- Carcinoma
- Autistic Disorder
- Tumor Angiogenesis
- Colorectal Neoplasms
- Colorectal Cancer
- Adenoma
- Malignant Neoplasm Of Breast
- Dysequilibrium Syndrome
- Granuloma
Interacting Proteins
- Ap2m1
- ITGB1
- ITGB7
- PXN
- TGFB1I1
Pathways
- Methylation
- Cell Proliferation
- Angiogenesis
- Pathogenesis
- Cell Adhesion
- Fertilization
- Immune Response
- Dna Methylation
- Localization
- Cell Migration
- Macromolecule Biosynthetic Process
- Biosynthetic Process
- Endothelial Cell Proliferation
PTMs
- Methylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ITGA4
bosterbio.com/bosterbio-gene-info-cards/ITGA4
References
PMID: 2788572 by Takada Y., et al. The primary structure of the alpha 4 subunit of VLA-4: homology to other integrins and a possible cell-cell adhesion function.
PMID: 1551405 by Rubio M., et al. A single mRNA encodes the alpha 150 and alpha 80/70 forms of the alpha subunit of VLA4.