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- Table of Contents
Facts about GRAM domain-containing protein 2A.
Human | |
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Gene Name: | GRAMD2A |
Uniprot: | Q8IUY3 |
Entrez: | 196996 |
Belongs to: |
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No superfamily |
GRAM domain-containing protein 2A
Mass (kDA):
40.249 kDA
Human | |
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Location: | 15q23 |
Sequence: | 15; NC_000015.10 (72159806..72197814, complement) |
Endoplasmic reticulum membrane; Single-pass membrane protein. Cell membrane; Peripheral membrane protein. Localizes to endoplasmic reticulum-plasma membrane contact sites (EPCS). Anchored at the ER, PM binding is mediated via GRAM domain and phosphatidylinositol lipid interaction. Localizes to distinct EPCS than GRAMD1A.
PMID: 29469807 by Besprozvannaya M., et al. GRAM domain proteins specialize functionally distinct ER-PM contact sites in human cells.