GPSM2 Antibodies

AND GPSM2 ELISA kits, GPSM2 Proteins

Many biological assays use antibodies to detect GPSM2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with GPSM2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop GPSM2 antibodies...

We validate the specificity of these antibodies to GPSM2 by testing them on tissues known to express GPSM2 positively and negatively. Browse below to find the GPSM2 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Previous: SEPTIN9 Next: CCDC106

GPSM2 Infographic by Boster Bio

All GPSM2 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-GPSM2 Antibody

Human, Mouse

$405
Cat # A04699
100ul

GPSM2 (NM_013296) Human Over-expression Lysate

Human

$628
Cat # LS029899
100 µg

GPSM2 Overview

Facts about G-protein-signaling modulator 2.

GPSM2 3D structure. Source: alphafold

G-protein-signaling modulator 2 (GPSM2)

Plays an important role in mitotic spindle pole organization via its interaction with NUMA1 (PubMed:11781568, PubMed:15632202, PubMed:21816348). Required for cortical dynein- dynactin complex recruitment during metaphase (PubMed:22327364).

Plays a role in metaphase spindle orientation (PubMed:22327364). Plays also an important role in asymmetric cell divisions (PubMed:21816348).

Gene Information

Human
Gene Name:	GPSM2
Uniprot:	P81274
Entrez:	29899

Family

Belongs to:

GPSM family

Alternative Names

deafness, autosomal recessive 82; DFNB82; G-protein signaling modulator 2; G-protein signalling modulator 2 (AGS3-like, C. elegans); G-protein-signaling modulator 2; LGNPins; Mosaic protein LGN; PINS

Molecular Weight

Mass (kDA):
76.662 kDA

Genomic Context


Human

Location:	1p13.3
Sequence:	1; NC_000001.11 (108875350..108934545)

Tissue Specificity

Ubiquitously expressed.

Subcellular Localizations

Cytoplasm. Cytoplasm, cell cortex. Cytoplasm, cytoskeleton, spindle pole. Lateral cell membrane. Localizes in the cytoplasm during interphase and at cell cortex during metaphase (PubMed:11781568, PubMed:15632202, PubMed:22074847). Colocalizes with NUMA1 to mitotic spindle poles (PubMed:11781568, PubMed:21816348). Localized at the central and lateral cell cortex regions in a RanGTP-dependent manner (PubMed:22327364). In horizontally retinal progenitor dividing cells, localized to the lateral cortical region. In vertically retinal progenitor dividing cells, localized at the polar cortical region

Diseases

Malignant Neoplasms
Deafness, Sensorineural, With Partial Agenesis Of The Corpus Callosum And Arachnoid Cysts
Complete Hearing Loss
Hypertensive Disease
Mutation, Out-of-frame
Deafness Congenital
Malignant Neoplasm Of Breast
Carcinogenesis
Dysplasia
Congenital Anomaly Of Brain
Neoplasms
Dihydropyrimidine Dehydrogenase Deficiency