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- Table of Contents
Facts about G-protein coupled receptor 55.
LPI induces Ca(2+) release from intracellular stores through the heterotrimeric G protein GNA13 and RHOA. Putative cannabinoid receptor.
Human | |
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Gene Name: | GPR55 |
Uniprot: | Q9Y2T6 |
Entrez: | 9290 |
Belongs to: |
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G-protein coupled receptor 1 family |
G protein-coupled receptor 55; Gm218; GPR55; G-protein coupled receptor 55
Mass (kDA):
36.637 kDA
Human | |
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Location: | 2q37.1 |
Sequence: | 2; NC_000002.12 (230907318..230961270, complement) |
Expressed in the caudate nucleus and putamen, but not detected in the hippocampus, thalamus, pons cerebellum, frontal cortex of the brain or in the liver. Expressed in osteoclasts and osteoblasts.
Cell membrane; Multi-pass membrane protein.
PMID: 9931487 by Sawzdargo M., et al. Identification and cloning of three novel human G protein-coupled receptor genes GPR52, PsiGPR53 and GPR55: GPR55 is extensively expressed in human brain.
PMID: 17765871 by Oka S., et al. Identification of GPR55 as a lysophosphatidylinositol receptor.