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- Table of Contents
2 Citations
2 Citations 4 Q&As
1 Citations
Facts about Glutamate decarboxylase 1.
Catalyzes the production of GABA.
.Human | |
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Gene Name: | GAD1 |
Uniprot: | Q99259 |
Entrez: | 2571 |
Belongs to: |
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group II decarboxylase family |
67kD); EC 4.1.1; FLJ45882; GAD1; GAD25; GAD67; glutamate decarboxylase 1 (brain, 67kDa); Glutamate decarboxylase 67 kDa isoform
Mass (kDA):
66.897 kDA
Human | |
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Location: | 2q31.1 |
Sequence: | 2; NC_000002.12 (170813210..170861151) |
Isoform 3 is expressed in pancreatic islets, testis, adrenal cortex, and perhaps other endocrine tissues, but not in brain.
PMID: 1549570 by Bu D.-F., et al. Two human glutamate decarboxylases, 65-kDa GAD and 67-kDa GAD, are each encoded by a single gene.
PMID: 8088791 by Bu D.-F., et al. The exon-intron organization of the genes (GAD1 and GAD2) encoding two human glutamate decarboxylases (GAD67 and GAD65) suggests that they derive from a common ancestral GAD.
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