GABRG3 Antibodies

AND GABRG3 ELISA kits, GABRG3 Proteins

Many biological assays use antibodies to detect GABRG3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with GABRG3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop GABRG3 antibodies...

We validate the specificity of these antibodies to GABRG3 by testing them on tissues known to express GABRG3 positively and negatively. Browse below to find the GABRG3 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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GABRG3 Infographic by Boster Bio

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GABRG3 (NM_033223) Human Over-expression Lysate

Human

$960
Cat # LS002567
100 µg

GABRG3 Overview

Facts about Gamma-aminobutyric acid receptor subunit gamma-3.

GABRG3 3D structure. Source: alphafold

Gamma-aminobutyric acid receptor subunit gamma-3 (GABRG3)

GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. .

Gene Information

Human
Gene Name:	GABRG3
Uniprot:	Q99928
Entrez:	2567

Family

Belongs to:

ligand-gated ion channel (TC 1.A.9) family

Alternative Names

GABA A R gamma 3; GABA(A) receptor subunit gamma-3; GABAAR gamma 3; GABAARg3; GABRG3; gamma-aminobutyric acid (GABA) A receptor, gamma 3; gamma-aminobutyric acid receptor subunit gamma-3

Molecular Weight

Mass (kDA):
54.289 kDA

Genomic Context


Human

Location:	15q12
Sequence:	15; NC_000015.10 (26971181..27541984)

Subcellular Localizations

Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.

Diseases

Autistic Disorder
Angelman Syndrome
Dysequilibrium Syndrome
Prader-willi Syndrome
Epilepsy, Generalized
Epilepsy
Nervousness
Child Development Disorders, Pervasive
Alzheimer's Disease
Dyskinetic Syndrome

Dyskinesia, Drug-induced
Acute Promyelocytic Leukemia
Chromosome Breakage
Neurofibrillary Tangles
Involuntary Movements

Pathways

Methylation
Response To Ethanol
Synaptic Transmission
Pathogenesis

PTMs

Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GABRG3

References

PMID: 8719414 by Hadingham K.L., et al. Expression and pharmacology of human GABAA receptors containing gamma 3 subunits.

PMID: 26566883 by Rafiullah R., et al. Homozygous missense mutation in the LMAN2L gene segregates with intellectual disability in a large consanguineous Pakistani family.