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- Table of Contents
Facts about Protein fuzzy homolog.
Proposed to serve as core part of the CPLANE (ciliogenesis and planar polarity effectors) complex involved in the recruitment of peripheral IFT-A proteins into basal bodies (PubMed:19877275, PubMed:19767740, PubMed:27158779). May regulate the morphogenesis of hair follicles which depends on functional main cilia (PubMed:20962855).
Mouse | |
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Gene Name: | Fuz |
Uniprot: | Q3UYI6 |
Entrez: | 70300 |
Belongs to: |
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fuzzy family |
FLJ22688; fuzzy homolog (Drosophila); FY; protein fuzzy homolog
Mass (kDA):
45.588 kDA
Mouse | |
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Location: | 7 B3|7 28.99 cM |
Sequence: | 7; |
Expressed in dermal and epidermal cells.
PMID: 19877275 by Heydeck W., et al. Planar cell polarity effector gene Fuzzy regulates cilia formation and Hedgehog signal transduction in mouse.
PMID: 19767740 by Gray R.S., et al. The planar cell polarity effector Fuz is essential for targeted membrane trafficking, ciliogenesis and mouse embryonic development.