EML1 Antibodies

AND EML1 ELISA kits, EML1 Proteins

Many biological assays use antibodies to detect EML1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with EML1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop EML1 antibodies...

We validate the specificity of these antibodies to EML1 by testing them on tissues known to express EML1 positively and negatively. Browse below to find the EML1 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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EML1 Infographic by Boster Bio

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EML1 (NM_004434) Human Over-expression Lysate

Human

$628
Cat # LS002009
100 µg

EML1 Overview

Facts about Echinoderm microtubule-associated protein-like 1.

EML1 3D structure. Source: alphafold

Echinoderm microtubule-associated protein-like 1 (EML1)

Modulates the meeting and organization of the microtubule cytoskeleton, and probably plays a role in regulating the orientation of the mitotic spindle and the orientation of the plane of cell division. Required for normal proliferation of neuronal progenitor cells in the developing brain and for normal brain growth.

Does not affect neuron migration per se. .

Gene Information

Human
Gene Name:	EML1
Uniprot:	O00423
Entrez:	2009

Family

Belongs to:

WD repeat EMAP family

Alternative Names

echinoderm microtubule associated protein like 1; ELP79; EMAP1; EMAP-1; EMAPechinoderm microtubule-associated protein-like 1; EMAPL1; EMAPLhuEMAP-1; FLJ45033; HuEMAP; HuEMAP-1

Molecular Weight

Mass (kDA):
89.861 kDA

Genomic Context


Human

Location:	14q32.2
Sequence:	14; NC_000014.9 (99737722..99942060)

Tissue Specificity

Ubiquitous; expressed in most tissues with the exception of thymus and peripheral blood lymphocytes.

Subcellular Localizations

Cytoplasm. Cytoplasm, perinuclear region. Cytoplasm, cytoskeleton. Detected in cytoplasmic punctae. Co-localizes with microtubules (PubMed:24859200). Enriched in perinuclear regions during interphase and in the region of spindle microtubules during metaphase. Enriched at the midzone during telophase and cytokinesis. Detected at growth cones in neurons (By similarity).

Diseases

Malabsorption Syndrome
Anemia
Proteinuria Of Undiagnosed Cause
Leukemia, T-cell
Tissue Adhesions
Myeloid Leukemia, Chronic
Precursor T-cell Lymphoblastic Leukemia-lymphoma
Acute Lymphocytic Leukemia
Carcinoma
Cancer Of Nasopharynx
Malignant Neoplasms
Myeloid Leukemia
Nasopharyngeal Neoplasms

Neoplasms
Nervousness
Leukemia
Dog Diseases
Anemia, Megaloblastic
Megaloblastic Anemia Due To Inborn Errors Of Metabolism
Precursor B-cell Lymphoblastic Leukemia-lymphoma

Interacting Proteins

ISG20L2

Pathways

Pathogenesis
Localization

PTMs

Phosphorylation

Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/EML1

References

PMID: 9226380 by Eudy J.D., et al. Isolation of a novel human homologue of the gene coding for echinoderm microtubule-associated protein (EMAP) from the Usher syndrome type 1a locus at 14q32.

PMID: 10521658 by Lepley D.M., et al. Sequence and expression patterns of a human EMAP-related protein-2 (HuEMAP-2).