DMAP1 Antibodies

AND DMAP1 ELISA kits, DMAP1 Proteins

Many biological assays use antibodies to detect DMAP1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with DMAP1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop DMAP1 antibodies...

We validate the specificity of these antibodies to DMAP1 by testing them on tissues known to express DMAP1 positively and negatively. Browse below to find the DMAP1 antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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DMAP1 Infographic by Boster Bio

All DMAP1 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-DMAP1 Antibody

Human, Mouse, Rat

IHC, WB

$405
Cat # A03688
100ul

DMAP1 (NM_019100) Human Recombinant Protein

$1249
Cat # PROTQ9NPF5
20 µg

Anti-DMAP1 Antibody Picoband®

Human, Mouse, Rat

ELISA, Flow Cytometry, IF, ICC, WB

$370
Cat # A03688-2
100 μg/vial

Anti-DMAP1 Rabbit Monoclonal Antibody

Human, Mouse, Rat

IF, ICC, WB

$370
Cat # M03688
100 μl/vial

DMAP1 (NM_019100) Human Over-expression Lysate

Human

$960
Cat # LS055929
100 µg

DMAP1 Overview

Facts about DNA methyltransferase 1-associated protein 1.

DMAP1 3D structure. Source: alphafold

DNA methyltransferase 1-associated protein 1 (DMAP1)

Involved in transcription repression and activation. Its interaction with HDAC2 may provide a mechanism for histone deacetylation in heterochromatin after replication of DNA at late firing origins.

Can also repress transcription independently of histone deacetylase activity. May especially potentiate DAXX- mediated repression of glucocorticoid receptor-dependent transcription.

Gene Information

Human
Gene Name:	DMAP1
Uniprot:	Q9NPF5
Entrez:	55929

Family

Belongs to:

No superfamily

Alternative Names

DNA methyltransferase 1 associated protein 1; DNA methyltransferase 1-associated protein 1; DNMAP1DNMT1-associated protein 1; DNMT1 associated protein 1; DNMTAP1; EAF2; FLJ11543; KIAA1425DKFZp686L09142; MEAF2; SWC4

Molecular Weight

Mass (kDA):
52.993 kDA

Genomic Context


Human

Location:	1p34.1
Sequence:	1; NC_000001.11 (44213471..44220673)

Subcellular Localizations

Nucleus. Cytoplasm. Targeted to replication foci throughout S phase by DNMT1.

Diseases

Neoplasms
Malignant Neoplasms
Carcinoma
Carcinogenesis
Leukemia
Malignant Paraganglionic Neoplasm
Hyperplasia
Malignant Neoplasm Of Breast
Lupus Erythematosus, Systemic
Cell Transformation, Neoplastic
Liver Carcinoma
Hepatitis
Malignant Neoplasm Of Lung

Cell Invasion
Schizophrenia
Malignant Neoplasm Of Stomach
Stomach Neoplasms
Neoplasm Metastasis
Autoimmunity
Hepatitis B

Pathways

Methylation
Dna Methylation
Demethylation
Cell Cycle
Dna Repair
Localization
Dna Replication
Gene Silencing
Dna Hypomethylation
Dna Demethylation
Cell Proliferation
Pathogenesis
Reverse Transcription

Histone Modification
Embryo Development
Histone Acetylation
Chromatin Remodeling
Cellular Localization
S Phase
Dna Hypermethylation

PTMs

Methylation
Demethylation
Phosphorylation

Acetylation
Deacetylation
Hydroxylation

Research Areas

Apoptosis
Chromatin Research
DNA Repair
MAP Kinase Signaling

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/DMAP1

References

PMID: 10888872 by Rountree M.R., et al. DNMT1 binds HDAC2 and a new co-repressor, DMAP1, to form a complex at replication foci.

PMID: 12963728 by Cai Y., et al. Identification of new subunits of the multiprotein mammalian TRRAP/TIP60-containing histone acetyltransferase complex.