CHEK1 Antibodies

AND CHEK1 ELISA kits, CHEK1 Proteins

Many biological assays use antibodies to detect CHEK1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CHEK1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CHEK1 antibodies...

We validate the specificity of these antibodies to CHEK1 by testing them on tissues known to express CHEK1 positively and negatively. Browse below to find the CHEK1 antibody that suites your experiment. We have 22 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CHEK1 Infographic by Boster Bio

All CHEK1 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-Chk1/CHEK1 Antibody Picoband®

15 Q&As

Human

Flow Cytometry, WB

$370
Cat # A01060
100 μg/vial

Anti-Phospho-Chk1 (S296) CHEK1 Rabbit Monoclonal Antibody

3 Q&As

Human

$370
Cat # P01060
100 μl

Anti-Chk1 CHEK1 Rabbit Monoclonal Antibody

17 Q&As

Human, Mouse, Rat

IP, IF, ICC, WB

$370
Cat # M01060-1
100 μl

Anti-Chk1 CHEK1 Rabbit Monoclonal Antibody

16 Q&As

Human

Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # M01060
100 μl

Chk1 Colorimetric Cell-Based ELISA Kit

Human, Mouse, Rat

ELISA

$480
Cat # EKC1112
1 kit, containing one 96-well plate and all necessary reagents

Chk1 (Phospho-Ser296) Colorimetric Cell-Based ELISA Kit

Human

ELISA

$540
Cat # EKC2149
1 kit, containing two 96-well plates and all necessary reagents

Chk1 (Phospho-Ser286) Colorimetric Cell-Based ELISA Kit

Human

ELISA

$540
Cat # EKC2235
1 kit, containing two 96-well plates and all necessary reagents

Chk1 (Phospho-Ser301) Colorimetric Cell-Based ELISA Kit

Human, Mouse, Rat

ELISA

$540
Cat # EKC2236
1 kit, containing two 96-well plates and all necessary reagents

Chk1 (Phospho-Ser280) Colorimetric Cell-Based ELISA Kit

Human

ELISA

$540
Cat # EKC2371
1 kit, containing two 96-well plates and all necessary reagents

Chk1 (Phospho-Ser317) Colorimetric Cell-Based ELISA Kit

Human, Mouse, Rat

ELISA

$540
Cat # EKC2372
1 kit, containing two 96-well plates and all necessary reagents

Anti-Chk1 (K274) CHEK1 Antibody

Human, Mouse, Rat

$405
Cat # A01060-1
100ul

Anti-Chk1 (N311) CHEK1 Antibody

Human, Mouse, Rat

IF, IHC

$405
Cat # A01060-2
100ul

Anti-Chk1 (phospho-S280) CHEK1 Antibody

Human, Mouse, Rat

$482
Cat # A01060S280
100ul

Anti-Chk1 (phospho-S317) CHEK1 Antibody

Human, Mouse, Rat

IHC, WB

$482
Cat # A01060S317
100ul

Anti-Chk1 (phospho-S345) CHEK1 Antibody

Human, Mouse, Rat

IHC, WB

$482
Cat # A01060S345
100ul

Anti-Chk1 (phospho-S286) CHEK1 Antibody

Human, Mouse, Rat

$482
Cat # A01060S286
100ul

Anti-CHK1 CHEK1 Antibody

Human, Mouse, Rat

IF, IHC, ICC, WB

$405
Cat # A01060-3
100ul

Anti-Chk1 (S291) CHEK1 Antibody

Human, Mouse, Rat

IHC

$405
Cat # A01060S291
100ul

Anti-Chk1 (Phospho-S296) CHEK1 Antibody

Human

IHC, WB

$405
Cat # A01060S296
100ul

Anti-Phospho-Chk1 (S301) CHEK1 Antibody

Human, Mouse, Rat

ELISA, IF, WB

$380
Cat # A01060S301
100ul

Chk1 (CHEK1) (NM_001274) Human Over-expression Lysate

Human

$628
Cat # LS001111
100 µg

Anti-Phospho-Chk1 (S280) Rabbit Monoclonal Antibody

Human

$370
Cat # M01060S280
100 µl/vial

CHEK1 Overview

Facts about Serine/threonine-protein kinase Chk1.

CHEK1 3D structure. Source: alphafold

Serine/threonine-protein kinase Chk1 (CHEK1)

Serine/threonine-protein kinase which is needed for checkpoint-mediated cell cycle arrest and activation of DNA repair in response to the presence of DNA damage or unreplicated DNA. This regulation is achieved by a range of mechanisms that collectively help to keep the integrity of the genome.

Binds to and phosphorylates CDC25A, CDC25B and CDC25C. Phosphorylation of CDC25A in'Ser-178' and'Thr-507' and phosphorylation of CDC25C in'Ser-216' creates binding sites for 14-3-3 proteins that inhibit CDC25A and CDC25C.

Gene Information

Human
Gene Name:	CHEK1
Uniprot:	O14757
Entrez:	1111

Family

Belongs to:

protein kinase superfamily

Alternative Names

Checkpoint, S. pombe, homolog of, 1; CHEK1; CHK1 (checkpoint, S.pombe) homolog; CHK1 checkpoint homolog (S. pombe); Chk1; CHK1serine/threonine-protein kinase Chk1; EC 2.7.11; EC 2.7.11.1

Molecular Weight

Mass (kDA):
54.434 kDA

Genomic Context


Human

Location:	11q24.2
Sequence:	11; NC_000011.10 (125624910..125676256)

Tissue Specificity

Expressed ubiquitously with the most abundant expression in thymus, testis, small intestine and colon.

Subcellular Localizations

Nucleus. Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Nuclear export is mediated at least in part by XPO1/CRM1. Also localizes to the centrosome specifically during interphase, where it may protect centrosomal CDC2 kinase from inappropriate activation by cytoplasmic CDC25B.