CACNG8 Antibodies

AND CACNG8 ELISA kits, CACNG8 Proteins

Many biological assays use antibodies to detect CACNG8, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CACNG8 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CACNG8 antibodies...

We validate the specificity of these antibodies to CACNG8 by testing them on tissues known to express CACNG8 positively and negatively. Browse below to find the CACNG8 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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CACNG8 Infographic by Boster Bio

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Anti-CCG8 CACNG8 Antibody

Human, Mouse, Rat

ELISA, WB

$380
Cat # A10890
100ul

CACNG8 Overview

Facts about Voltage-dependent calcium channel gamma-8 subunit.

CACNG8 3D structure. Source: alphafold

Voltage-dependent calcium channel gamma-8 subunit (CACNG8)

Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs).

Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Does not reveal subunit-specific AMPA receptor regulation and regulates all AMPAR subunits.

Gene Information

Human
Gene Name:	CACNG8
Uniprot:	Q8WXS5
Entrez:	59283

Family

Belongs to:

PMP-22/EMP/MP20 family

Alternative Names

CACNG6; calcium channel, voltage-dependent, gamma subunit 8; FLJ16240; FLJ30598; Neuronal voltage-gated calcium channel gamma-8 subunit; voltage-dependent calcium channel gamma-8 subunit

Molecular Weight

Mass (kDA):
43.313 kDA

Genomic Context


Human

Location:	19q13.42
Sequence:	19; NC_000019.10 (53962937..53990215)

Tissue Specificity

Detected in heart left ventricle.

Subcellular Localizations

Cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic density membrane.

PTMs

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CACNG8

References

PMID: 11738816 by Chu P.-J., et al. Calcium channel gamma subunits provide insights into the evolution of this gene family.

PMID: 11170751 by Burgess D.L., et al. A cluster of three novel Ca(2+) channel gamma subunit genes on chromosome 19q13.4: evolution and expression profile of the gamma subunit gene family.