Complement C4-B Antibodies

AND C4B ELISA kits, Complement C4-B Proteins

Many biological assays use antibodies to detect Complement C4-B, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Complement C4-B in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Complement C4-B antibodies...

We validate the specificity of these antibodies to Complement C4-B by testing them on tissues known to express C4B positively and negatively. Browse below to find the C4B antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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C4B Infographic by Boster Bio

All C4B Products

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Product

Figures

Specificity

Applications

Price

Anti-Complement 4d (C4d) (Acute Humoral Rejection Marker) C4A Monoclonal Antibody

5 Q&As

Human

IF, IHC

$486
Cat # M01095
100ug/vial

Anti-Complement C4B (C4B) Mouse Monoclonal Antibody [Clone ID: OTI1B2]

Human

$523
Cat # M04592
100 µl

C4B Overview

Facts about Complement C4-B.

C4B 3D structure. Source: alphafold

Complement C4-B (C4B)

Non-enzymatic part of the C3 and C5 convertases and thus essential for the propagation of the classical complement pathway. Covalently binds to immunoglobulins and immune complexes and enhances the solubilization of immune aggregates and the clearance of IC through CR1 on erythrocytes.

C4A isotype is accountable for effective binding to form amide bonds with resistant aggregates or protein antigens, while C4B isotype catalyzes the transacylation of the thioester carbonyl group to form ester bonds with carbohydrate antigens. .

Gene Information

Human
Gene Name:	C4B
Uniprot:	P0C0L5
Entrez:	721

Family

Belongs to:

No superfamily

Alternative Names

basic C4; Basic complement C4; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 3; C4B1; C4B12; C4B2; C4B3; C4FMGC164979; CH; Chido form of C4; CO4C4B5; complement C4-B; complement C4B1a; complement component 4B (Chido blood group); complement component 4B; CPAMD3FLJ60561; EC 2.1.1.144; EC 2.7.11

Molecular Weight

Mass (kDA):
192.751 kDA

Genomic Context


Human

Location:	6p21.33
Sequence:	6; NC_000006.12 (32014795..32035418)

Tissue Specificity

Complement component C4 is expressed at highest levels in the liver, at moderate levels in the adrenal cortex, adrenal medulla, thyroid gland,and the kidney, and at lowest levels in the heart, ovary, small intestine, thymus, pancreas and spleen. The extra-hepatic sites of expression may be important for the local protection and inflammatory response.