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- Table of Contents
Facts about B-cell CLL/lymphoma 9-like protein.
Plays a role in tumorigenesis. Enhances the neoplastic transforming activity of CTNNB1.
Mouse | |
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Gene Name: | Bcl9l |
Uniprot: | Q67FY2 |
Entrez: | 80288 |
Belongs to: |
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BCL9 family |
B-cell CLL/lymphoma 9-like protein; B-cell CLL/lymphoma 9-like; B-cell lymphoma 9-like protein; Bcl92; Bcl9-2; BCL9-like protein; DLNB11; DLNB11BCL9-2; nuclear co-factor of beta-catenin signalling; Protein BCL9-2
Mass (kDA):
156.68 kDA
Mouse | |
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Location: | 9|9 A5.2 |
Sequence: | 9; |
Expressed in kidney, liver, lung, testis, brain, spleen, heart and skeletal muscle. Highly expressed in numerous colorectal tumors compared to corresponding non-cancerous tissues.
PMID: 15574752 by Adachi S., et al. Role of a BCL9-related beta-catenin-binding protein, B9L, in tumorigenesis induced by aberrant activation of Wnt signaling.
PMID: 15371335 by Brembeck F.H., et al. Essential role of BCL9-2 in the switch between beta-catenin's adhesive and transcriptional functions.