Anoctamin-10 Antibodies

AND ANO10 ELISA kits, Anoctamin-10 Proteins

Many biological assays use antibodies to detect Anoctamin-10, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Anoctamin-10 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Anoctamin-10 antibodies...

We validate the specificity of these antibodies to Anoctamin-10 by testing them on tissues known to express ANO10 positively and negatively. Browse below to find the ANO10 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ANO10 Infographic by Boster Bio

All ANO10 Products

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Product

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Specificity

Applications

Price

Anti-Anoctamin-10 ANO10 Antibody

Human

ELISA, WB

$380
Cat # A06919
100ul

TMEM16K (ANO10) (NM_018075) Human Over-expression Lysate

Human

$960
Cat # LS055129
100 µg

ANO10 Overview

Facts about Anoctamin-10.

ANO10 3D structure. Source: alphafold

Anoctamin-10 (ANO10)

Doesn't exhibit calcium-activated chloride channel (CaCC) activity. Can inhibit the action of ANO1.

Gene Information

Human
Gene Name:	ANO10
Uniprot:	Q9NW15
Entrez:	55129

Family

Belongs to:

anoctamin family

Alternative Names

anoctamin 10; FLJ10375; MGC47890; Transmembrane protein 16KTMEM16Kanoctamin-10

Molecular Weight

Mass (kDA):
76.329 kDA

Genomic Context


Human

Location:	3p22.1-p21.33
Sequence:	3; NC_000003.12 (43365848..43691594, complement)

Tissue Specificity

Highly expressed in the brain. Intermediate levels in the retina and heart and low levels in the placenta, liver, lung, duodenum, kidney, testis and spleen. In brain areas, highest expression in the frontal and occipital cortices and in the cerebellum. Lower expression in the fetal brain than in the adult brain.

Subcellular Localizations

Cell membrane; Multi-pass membrane protein. Shows predominantly an intracellular localization with a weak expression in the cell membrane.

Diseases

Ataxia
Cerebellar Ataxia
Cystic Fibrosis
Malnutrition
Neurodegenerative Disorders
Bleeding Tendency
Dystrophy
Fibrosis
Maculopathy
Malignant Neoplasms

Hemorrhage
Impaired Cognition
Ataxia, Spinocerebellar
Muscular Dystrophy

Pathways

Transport
Iodide Transport

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ANO10

References

PMID: 20056604 by Schreiber R., et al. Expression and function of epithelial anoctamins.

PMID: 21642943 by Duran C., et al. Physiological roles and diseases of Tmem16/Anoctamin proteins: are they all chloride channels?