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- Table of Contents
Facts about DNA oxidative demethylase ALKBH2.
Has strong taste for double- stranded DNA. Has low efficiency with single-stranded substrates.
Human | |
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Gene Name: | ALKBH2 |
Uniprot: | Q6NS38 |
Entrez: | 121642 |
Belongs to: |
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alkB family |
2OG-Fe(II) oxy DC1; ABH2FLJ99103; alkB, alkylation repair homolog 2 (E. coli); Alkylated DNA repair protein alkB homolog 2; alpha-ketoglutarate-dependent dioxygenase alkB homolog 2; EC 1.14.11.-; MGC90512; Oxy DC1
Mass (kDA):
29.322 kDA
Human | |
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Location: | 12q24.11 |
Sequence: | 12; NC_000012.12 (109088188..109093631, complement) |
Detected in colon, small intestine, ovary, testis, prostate, skeletal muscle, heart, liver and urinary bladder.
Nucleus. Detected in replication foci during S-phase.
PMID: 17979886 by Tsujikawa K., et al. Expression and sub-cellular localization of human ABH family molecules.
PMID: 12486230 by Duncan T., et al. Reversal of DNA alkylation damage by two human dioxygenases.