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1 Q&As
Facts about Cytosolic carboxypeptidase 3.
Also removes gene-encoded polyglutamates or polyaspartates in the carboxy-terminus of target proteins like MYLK. Doesn't show detyrosinase or deglycylase activities from the carboxy- terminus of tubulin.
Mouse | |
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Gene Name: | Agbl3 |
Uniprot: | Q8CDP0 |
Entrez: | 76223 |
Belongs to: |
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peptidase M14 family |
Cytosolic carboxypeptidase 3
Mass (kDA):
116.378 kDA
Mouse | |
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Location: | 6|6 B1 |
Sequence: | 6; |
Widely expressed. Expressed abundantly in tissues with m otile cilia such as testis, lung and trachea. Abundantly expressed in pituitary and kidney, moderately expressed in brain, eye, fat, pancreas, stomach, and adrenal.
PMID: 17244818 by Kalinina E., et al. A novel subfamily of mouse cytosolic carboxypeptidases.
PMID: 25103237 by Tort O., et al. The cytosolic carboxypeptidases CCP2 and CCP3 catalyze posttranslational removal of acidic amino acids.