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Product Info Summary
| SKU: | A12927 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, IHC-P, WB |
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Product info
Product Name
Anti-Synaptotagmin-like protein 5 SYTL5 Antibody
SKU/Catalog Number
A12927
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-Synaptotagmin-like protein 5 SYTL5 Antibody (Catalog # A12927). Tested in ELISA, WB, IHC-P applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
SYTL5 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-Synaptotagmin-like protein 5 SYTL5 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A12927)
Host
Rabbit
Contents
SYTL5 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
SYTL5 antibody was raised against a 17 amino acid synthetic peptide near the amino terminus of human SYTL5. The immunogen is located within amino acids 30 - 80 of SYTL5.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
Multiple isoforms of SYTL5 are known to exist. SYTL5 antibody is predicted to not cross-react with other SYTL protein family members.
Reactive Species
A12927 is reactive to SYTL5 in Human, Mouse, Rat
Reconstitution
Observed Molecular Weight
68 kDa
Calculated molecular weight
81523 MW
Background of SYTL5
SYTL5 belongs to the synaptotagmin-like (Slp) protein family, which contains a unique Slp homolog domain (SHD) at the N-terminus. The SHD functions as a binding site for Rab27A, which plays a role in protein transport. Expression of SYTL5 is restricted to placenta and liver, suggesting that it might be involved in Rab27A-dependent membrane trafficking in specific tissues. Several members of the synaptotagmin family are calcium-sensing vesicle-fusion proteins as mediators of cell migration. SYTL7 & SYTL5 were positive regulators of chemotaxis, whereas SYTL2 was a negative regulator of chemotaxis.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A12927 is guaranteed for ELISA, IHC-P, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
SYTL5 antibody can be used for detection of SYTL5 by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL.
Antibody validated: Western Blot in human samples and Immunohistochemistry in rat samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of SYTL5 in Hela cell lysate with SYTL5 antibody at (A) 1 and (B) 2 μg/mL .
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Immunohistochemistry of SYTL2 in rat liver tissue with SYTL2 antibody at 5 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For SYTL5 (Source: Uniprot.org, NCBI)
Gene Name
SYTL5
Full Name
Synaptotagmin-like protein 5
Weight
81523 MW
Alternative Names
slp5, SLP5, Synaptotagmin-like protein 5 SYTL5 slp5 synaptotagmin like 5 synaptotagmin-like protein 5|exophilin 9
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on SYTL5, check out the SYTL5 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for SYTL5: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Synaptotagmin-like protein 5 SYTL5 Antibody (A12927)
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