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Product Info Summary
| SKU: | A16432 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, IHC-P, WB |
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Product info
Product Name
Anti-Probable ribonuclease ZC3H12B ZC3H12B Antibody
SKU/Catalog Number
A16432
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-Probable ribonuclease ZC3H12B ZC3H12B Antibody (Catalog # A16432). Tested in ELISA, WB, IHC-P applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
ZC3H12B antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-Probable ribonuclease ZC3H12B ZC3H12B Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A16432)
Host
Rabbit
Contents
ZC3H12B Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
ZC3H12B antibody was raised against a 17 amino acid synthetic peptide near the amino terminus of human ZC3H12B. The immunogen is located within the first 50 amino acids of ZC3H12B.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
SHISA4 antibody is predicted to not cross-react with other SHISA protein family members.
Reactive Species
A16432 is reactive to ZC3H12B in Human, Mouse, Rat
Reconstitution
Observed Molecular Weight
68 kDa
Calculated molecular weight
94205 MW
Background of ZC3H12B
ZC3H12B, also known as MCPIP2, is a member of a family of novel CCCH-zinc finger proteins that regulate macrophage activation and may be involved in host immunity and inflammatory diseases. The function of ZC3H12B is not well understood. Unlike other members of the ZC3H12 family, ZC3H12B has a RasGEF domain at the C-terminal of the zinc finger motif, suggesting its potential involvement in Ras-mediated signal transduction. It is highly expressed in brain, thymus, and testis, but unlike ZC3H12A and ZC3H12C, not expressed in macrophages after treatment with lipopolysaccharide (LPS).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A16432 is guaranteed for ELISA, IHC-P, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
ZC3H12B antibody can be used for detection of ZC3H12B by Western blot at 1 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL.
Antibody validated: Western Blot in mouse samples and Immunohistochemistry in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of ZC3H12B in mouse brain tissue lysate with ZC3H12B antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.
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Immunohistochemistry of ZC3H12B in human brain tissue with ZC3H12B antibody at 5 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For ZC3H12B (Source: Uniprot.org, NCBI)
Gene Name
ZC3H12B
Full Name
Probable ribonuclease ZC3H12B
Weight
94205 MW
Superfamily
ZC3H12 family
Alternative Names
MCPIP2, CXorf32, MCPIP2, Probable ribonuclease ZC3H12B, MCP-induced protein 2 ZC3H12B CXorf32, MCPIP2 zinc finger CCCH-type containing 12B probable ribonuclease ZC3H12B|MCP-induced protein 2|zinc finger CCCH domain-containing protein 12B
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on ZC3H12B, check out the ZC3H12B Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for ZC3H12B: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Probable ribonuclease ZC3H12B ZC3H12B Antibody (A16432)
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