Anti-GADD45GIP1/Crif1 Antibody

Product Name

Anti-GADD45GIP1/Crif1 Antibody

View all CRIF1 Antibodies

SKU/Catalog Number

A06696

Size

100 µl

Form

Liquid

Description

Boster Bio Anti-GADD45GIP1/Crif1 Antibody (Catalog # A06696). Tested in IHC applications. This antibody reacts with Human.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-GADD45GIP1/Crif1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A06696)

Host

Rabbit

Contents

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from internal of human GADD45GIP1.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross reactivity with other proteins.

Reactive Species

A06696 is reactive to GADD45GIP1 in Human

Reconstitution

Restore with deionized water (or equivalent) for reconstitution volume of 100 µL

Calculated molecular weight

25384 MW

Background of CRIF1

Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity. May play a role in mitochondrial protein synthesis.

Goernemann J., Virology 303:69-78(2002).
Chung H.K., J. Biol. Chem. 278:28079-28088(2003).
The MGC Project Team, Genome Res. 14:2121-2127(2004).

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

View more details

Applications

A06696 is guaranteed for IHC Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Immunohistochemistry: 1:50~1:100

Validation Images & Assay Conditions

Gene/Protein Information For GADD45GIP1 (Source: Uniprot.org, NCBI)

Alternative Names

Growth arrest and DNA damage-inducible proteins-interacting protein 1;39S ribosomal protein L59, mitochondrial;MRP-L59;CKII beta-associating protein;CR6-interacting factor 1;CRIF1;Papillomavirus L2-interacting nuclear protein 1;PLINP;PLINP-1;p53-responsive gene 6 protein;GADD45GIP1;MRPL59, PLINP1, PRG6; GADD45GIP1 CKBBP2, CKbetaBP2, CRIF1, MRP-L59, PLINP, PLINP-1, PRG6, Plinp1 GADD45G interacting protein 1 growth arrest and DNA damage-inducible proteins-interacting protein 1|39S ribosomal protein L59, mitochondrial|CKII beta binding protein 2|CKII beta-associating protein|CR6 interacting factor 1|growth arrest and DNA-damage-inducible, gamma interacting protein 1|growth arrest- and DNA damage-inducible GADD45G-interacting protein|mitochondrial large ribosomal subunit protein CRIF1|mitochondrial large ribosomal subunit protein mL64|p53-responsive gene 6 protein|papillomavirus L2 interacting nuclear protein 1

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

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