Anti-Cytokeratin 18 (KRT18) Monoclonal Antibody

SKU M01357
Size 100ug/vial
Reactivity Bovine, Canine, Equine, Goat, Hamster, Human, Monkey, Mouse, Pig, Rat
Clonality Monoclonal
Clone Number C-04; same as Ks18.04
Host Mouse
Applications IHC

Overview

Product Name Anti-Cytokeratin 18 (KRT18) Monoclonal Antibody
SKU/Catalog Number M01357
Storage & Handling Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months.
Size 100ug/vial
Description Mouse Monoclonal antibody for Cytokeratin 18/KRT18 detection. Tested positive for IF, IHC in Bovine, Canine, Equine, Goat, Hamster, Human, Monkey, Mouse, Pig, Rat
Cite This Product Anti-Cytokeratin 18 (KRT18) Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M01357)
Host Mouse
Contents/Buffer Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Form Liquid
Immunogen Cytoskeletal preparation extracted from the human vulvar squamous carcinoma cell line A431
Reactivity Bovine, Canine, Equine, Goat, Hamster, Human, Monkey, Mouse, Pig, Rat

Assay Details

Assay Dilutions Overview

Concentration: 0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Immunohistology (Formalin-fixed) (0.5-1ug/ml for 30 min at RT)
Immunofluorescence (1-2ug/ml)

Images And Assay Conditions

Formalin-fixed, paraffin-embedded human Thyroid Carcinoma stained with Cytokeratin 18 Monoclonal Antibody (C-04).

Target Info

Protein Target Info (Source: Uniprot.org)

Uniprot Id P05783
Gene Name KRT18
Protein Name Keratin, type I cytoskeletal 18
Tissue Specificity Expressed in colon, placenta, liver and very weakly in exocervix. Increased expression observed in lymph nodes of breast carcinoma. .
Alternative Names Keratin, type I cytoskeletal 18;Cell proliferation-inducing gene 46 protein;Cytokeratin-18;CK-18;Keratin-18;K18;KRT18;CYK18;PIG46;
Subcellular Localization Cytoplasm, perinuclear region. Nucleus, nucleolus.
Molecular Weight 48058 MW

*if product is indicated to react with multiple species, protein info is based on the human gene.

Ontology

Protein Function Involved in the uptake of thrombin-antithrombin complexes by hepatic cells (By similarity). When phosphorylated, plays a role in filament reorganization. Involved in the delivery of mutated CFTR to the plasma membrane. Together with KRT8, is involved in interleukin-6 (IL-6)-mediated barrier protection. .
Research Areas Bovine, Canine, Equine, Goat, Hamster, Human, Monkey, Mouse, Pig, Rat

*You can search these to find other products in these research areas.

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In stock
Order Product
M01357
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$299.00

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Publications

Small intestinal intraepithelial lymphocytes expressing CD8 and T cell receptor %u03B3%u03B4 are involved in bacterial clearance during Salmonella enterica serovar Typhimurium %u2026
The Paracrine Effect of Transplanted Human Amniotic Epithelial Cells on Ovarian Function Improvement in a Mouse Model of Chemotherapy-Induced Primary Ovarian Insufficiency
Comparison of the effect of recombinant bovine wild and mutant lipopolysaccharide-binding protein in lipopolysaccharide-challenged bovine mammary epithelial cells
Hu J, Zhou Z, Shi S, Zhu X, Wang X, Zhang W, Hu S, Qian H, Xu W. Oncol Lett. 2013 Jan;5(1):179-184. Epub 2012 Oct 30. Mesenchymal Stem-Like Cells Isolated From Human Esophageal Carcinoma And Adjacent Non-Cancerous Tissues.
Xu B,, Jin X,, Min L, Li Q,, Deng L,, Wu H, Lin G, Chen L, Zhang H, Li C, Wang L, Zhu J,, Wang W,, Chu F,, Shen J,, Li H, Mao J,. Oncotarget. 2015 Feb 10;6(4):2434-50. Chloride Channel-3 Promotes Tumor Metastasis By Regulating Membrane Ruffling An...
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