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Product Info Summary
| SKU: | A16305 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse |
| Host: | Rabbit |
| Application: | ELISA, IHC-P, WB |
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Product info
Product Name
Anti-CTRP2 C1QTNF2 Antibody
SKU/Catalog Number
A16305
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-CTRP2 C1QTNF2 Antibody (Catalog # A16305). Tested in ELISA, WB, IHC-P applications. This antibody reacts with Human, Mouse.
Storage & Handling
CTRP2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-CTRP2 C1QTNF2 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A16305)
Host
Rabbit
Contents
CTRP2 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
Rabbit CTRP2 polyclonal antibody was raised against a 16 amino acid synthetic peptide from near the center of human CTRP2. The immunogen is located within amino acids 140 - 190 of CTRP2.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
These proteins are often highly modified post-translationally and migrate in SDS-PAGE at positions other than their predicted size.
Reactive Species
A16305 is reactive to C1QTNF2 in Human, Mouse
Reconstitution
Observed Molecular Weight
68 kDa
Calculated molecular weight
29952 MW
Background of CTRP2
Adipose tissue of an organism plays a major role in regulating physiologic and pathologic processes such as metabolism and immunity by producing and secreting a variety of bioactive molecules termed adipokines. One highly conserved family of adipokines is adiponectin/ACRP30 and its structural and functional paralogs, the C1q/tumor necrosis factor-alpha-related proteins (CTRPs) 1-7. Unlike adiponectin, which is expressed exclusively by differentiated adipocytes, the CTRPs are expressed in a wide variety of tissues. These proteins are thought to act mainly on liver and muscle tissue to control glucose and lipid metabolism. An analysis of the crystal structure of adiponectin revealed a structural and evolutionary link between TNF and C1q-containing proteins, suggesting that these proteins arose from a common ancestral innate immunity gene. Of the CTRPs, CTRP2 is most similar structurally and functionally to adiponectin. Recombinant CTRP2 rapidly activated AMPK and MAPK in cultured C2C12 cells, leading to increased glycogen accumulation and fatty acid oxidation.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A16305 is guaranteed for ELISA, IHC-P, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
CTRP2 polyclonal antibody can be used for the detection of CTRP2 by Western blot at 1 - 4 μg/mL. Antibody can also be used for immunohistochemistry starting at 10 μg/mL.
Antibody validated: Western Blot in mouse samples and Immunohistochemistry in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of CTRP2 in 3T3 (Balb) cell lysate with CTRP2 (IN) antibody at (A) 1
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Immunohistochemical staining of human brain tissue using CTRP2 antibody at 10 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For C1QTNF2 (Source: Uniprot.org, NCBI)
Gene Name
C1QTNF2
Full Name
Complement C1q tumor necrosis factor-related protein 2
Weight
29952 MW
Alternative Names
CTRP2, zacrp2, CTRP2, UNQ6349/PRO21054, Complement C1q tumor necrosis factor-related protein 2
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on C1QTNF2, check out the C1QTNF2 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for C1QTNF2: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-CTRP2 C1QTNF2 Antibody (A16305)
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