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Product Info Summary
| SKU: | A03177 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, ICC, WB |
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Product info
Product Name
Anti-Chondroadherin CHAD Antibody
View all Chondroadherin Antibodies
SKU/Catalog Number
A03177
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-Chondroadherin CHAD Antibody (Catalog # A03177). Tested in ELISA, WB, ICC applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
Chondroadherin antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Cite This Product
Anti-Chondroadherin CHAD Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A03177)
Host
Rabbit
Contents
Chondroadherin antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
Chondroadherin antibody was raised against a 17 amino acid peptide near the carboxy terminus of human Chondroadherin. The immunogen is located within the last 50 amino acids of Chondroadherin.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
Chondroadherin antibody is human and mouse reactive. Chondroadherin antibody is predicted to not cross-react with CHADL protein.
Reactive Species
A03177 is reactive to CHAD in Human, Mouse, Rat
Reconstitution
Observed Molecular Weight
68 kDa
Calculated molecular weight
40476 MW
Background of Chondroadherin
Chondroadherin, also known as CHAD or SLRR4A, belongs to the small leucine-rich proteoglycan (SLRP) family and class IV subfamily and plays a significant role in the regulation of chondrocyte growth and proliferation (1,2). It localizes to the extracellular matrix and contains nine tandem leucine repeats as well as N-terminal and C-terminal leucine rich domains (2-4). Chondroadherin is implicated in the adhesion of fibroblasts, osteoblasts and chondrocytes, which is mediated by interactions with Integrin alpha2 beta1 (2,4,5).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A03177 is guaranteed for ELISA, ICC, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
Chondroadherin antibody can be used for detection of Chondroadherin by Western blot at 1 - 2 μg/ml. Antibody can also be used for immunocytochemistry starting at 5 μg/mL.
Antibody validated: Western Blot in mouse samples and Immunocytochemistry in mouse samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of Chondroadherin in 3T3 cell lysate with Chondroadherin antibody at 1 μg/ml.
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Immunocytochemistry of Chondroadherin in 3T3 cells with Chondroadherin antibody at 5 μg/ml.
Protein Target Info & Infographic
Gene/Protein Information For CHAD (Source: Uniprot.org, NCBI)
Gene Name
CHAD
Full Name
Chondroadherin
Weight
40476 MW
Superfamily
small leucine-rich proteoglycan (SLRP) family
Alternative Names
Cartilage leucine-rich protein, CHAD, SLRR4A CHAD SLRR4A chondroadherin chondroadherin|cartilage leucine-rich protein|chondroadherin proteoglycan
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on CHAD, check out the CHAD Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for CHAD: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Chondroadherin CHAD Antibody (A03177)
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