Anti-Cathepsin L Ctsl Antibody (Monoclonal, 33/2)

Cathepsin L antibody

Boster Bio Anti-Cathepsin L Ctsl Antibody (Monoclonal, 33/2) catalog # MA1014. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat.

Product Info Summary

SKU: MA1014
Size: 100 μg/vial
Reactive Species: Human, Mouse, Rat
Host: Mouse
Application: IHC, WB

Product Name

Anti-Cathepsin L Ctsl Antibody (Monoclonal, 33/2)

View all Cathepsin L Antibodies

SKU/Catalog Number

MA1014

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-Cathepsin L Ctsl Antibody (Monoclonal, 33/2) catalog # MA1014. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-Cathepsin L Ctsl Antibody (Monoclonal, 33/2) (Boster Biological Technology, Pleasanton CA, USA, Catalog # MA1014)

Host

Mouse

Contents

Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative.

Clonality

Monoclonal

Clone Number

33/2

Isotype

Mouse IgG1

Immunogen

Procathepsin L isolated from the human lung cancer cell line EPLC 32M1.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross-reactivity with other proteins

Reactive Species

MA1014 is reactive to CTSL in Human, Mouse, Rat

Applications

MA1014 is guaranteed for IHC, WB Boster Guarantee

Observed Molecular Weight

25 kDa

Calculated molecular weight

37.564kDa

Background of Cathepsin L

Cathepsin L is a lysosomal cysteine proteinase with a major role in intracellular protein catabolism. It also shows the most potent collagenolytic and elastinolytic activity in vitro of any of the cathepsins. Cathepsin L has been implicated in pathologic processes including myofibril necrosis in myopathies and in myocardial ischemia, and in the renal tubular response to proteinuria. Human liver cathepsin L consists of a heavy chain of about 25 kD and a light chain of about 5 kD. The gene is mapped to 9q21-q22. Cathepsin L is required for endothelial progenitor cell-induced neovascularization.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

View more details

Innovating Scientists Reward

If you are the first to review this product, or if you have results for a special sample, species or application this product is not validated in, share your results with us and receive product credits you can use towards any Boster products! Applicable to all scientists worldwide.

Submit A Review

Reconsitution

Add 1ml of PBS buffer will yield a concentration of 100ug/ml.

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Immunohistochemistry (Frozen Section), 4μg/ml, Human, mouse, rat, -
Western blot, 0.1-0.5μg/ml, Human, mouse, rat

Validation Images & Assay Conditions

Gene/Protein Information For CTSL (Source: Uniprot.org, NCBI)

Gene Name

CTSL

Full Name

Cathepsin L1

Weight

37.564kDa

Superfamily

peptidase C1 family

Alternative Names

Cathepsin L; cathepsin L1; CATL; CTSL; CTSL1; CTSLEC 3.4.22.15; EC 3.4.22; FLJ31037; Major excreted protein; MEP CTSL CATL1, MEP, CTSL cathepsin L procathepsin L|cathepsin L1|major excreted protein

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on CTSL, check out the CTSL Infographic

CTSL infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for CTSL: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

Hello CJ!

No publications found for MA1014

*Do you have publications using this product? Share with us and receive a reward. Ask us for more details.

Have you used Anti-Cathepsin L Ctsl Antibody (Monoclonal, 33/2)?

Submit a review and receive an Amazon gift card.

  • $25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
  • $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit A Review

Be the first to review Anti-Cathepsin L Ctsl Antibody (Monoclonal, 33/2)

*The first user to submit a review for a product is eligible for Boster's Innovating Scientists Reward, which gives product credits. This is in addition to the gift card reward.

Have a question?

Find answers in Q&As, reviews.

Can't find your answer?

Submit your question

3 Customer Q&As for Anti-Cathepsin L Ctsl Antibody (Monoclonal, 33/2)

Question

Is this MA1014 anti-Cathepsin L antibody (Monoclonal, 33/2) reactive to the isotypes of CTSL1?

Verified Customer

Verified customer

Asked: 2020-01-14

Answer

The immunogen of MA1014 anti-Cathepsin L antibody (Monoclonal, 33/2) is Procathepsin L isolated from the human lung cancer cell line EPLC 32M1. Could you tell me which isotype you are interested in so I can help see if the immunogen is part of this isotype?

Boster Scientific Support

Answered: 2020-01-14

Question

We are currently using anti-Cathepsin L antibody (Monoclonal, 33/2) MA1014 for mouse tissue, and we are happy with the IHC results. The species of reactivity given in the datasheet says human, mouse, rat. Is it possible that the antibody can work on goat tissues as well?

Verified Customer

Verified customer

Asked: 2019-07-17

Answer

The anti-Cathepsin L antibody (Monoclonal, 33/2) (MA1014) has not been tested for cross reactivity specifically with goat tissues, but there is a good chance of cross reactivity. We have an innovator award program that if you test this antibody and show it works in goat you can get your next antibody for free. Please contact me if I can help you with anything.

Boster Scientific Support

Answered: 2019-07-17

Question

Is a blocking peptide available for product anti-Cathepsin L antibody (Monoclonal, 33/2) (MA1014)?

K. Johnson

Verified customer

Asked: 2016-05-11

Answer

We do provide the blocking peptide for product anti-Cathepsin L antibody (Monoclonal, 33/2) (MA1014). If you would like to place an order for it please contact [email protected] and make a special request.

Boster Scientific Support

Answered: 2016-05-11

Order DetailsPrice
MA1014

100μg

$370
MA1014-10ug

10μg sample (liquid)

$99
MA1014-Biotin

100 μg Biotin conjugated

$570
MA1014-Cy3

100 μg Cy3 conjugated

$570
MA1014-Dylight488

100 μg Dylight488 conjugated

$570
MA1014-Dylight550

100 μg Dylight550 conjugated

$570
MA1014-Dylight594

100 μg Dylight594 conjugated

$570
MA1014-FITC

100 μg FITC conjugated

$570
MA1014-HRP

100 μg HRP conjugated

$570
MA1014-APC

100 μg APC conjugated

$670
MA1014-PE

100 μg PE conjugated

$670
MA1014-carrier-free

Carrier Free

$370

More conjugates/formats

Free Secondary Antibody

Choose an option to show lead time.
Get A Quote
Eddy test
In stock
Order Product
MA1014
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$370.00

Troubleshooting

troubleshooting-box-image

Download troubleshooting handbooks for IHC, Western blot and ELISA for FREE.

Download Free PDFs Now

Boster Guarantee

Guaranteed product quality

Guaranteed product quality

We promise all of our products perform as described in datasheets.