Click image to see more details
Product Info Summary
| SKU: | A02471-1 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, IF, IHC-P, WB |
Customers Who Bought This Also Bought
Product info
Product Name
Anti-Betatrophin ANGPTL8 Antibody
View all Angiopoietin-like protein 8/Betatrophin Antibodies
SKU/Catalog Number
A02471-1
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-Betatrophin ANGPTL8 Antibody (Catalog # A02471-1). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
Betatrophin antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Cite This Product
Anti-Betatrophin ANGPTL8 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A02471-1)
Host
Rabbit
Contents
Betatrophin antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
Betatrophin antibody was raised against a 16 amino acid peptide near the amino terminus of human Betatrophin. The immunogen is located within amino acids 40 - 90 of Betatrophin.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
Betatrophin antibody is human, mouse and rat reactive. At least three isoforms of Betatrophin are known to exist; this antibody will detect the two largest isoforms.
Reactive Species
A02471-1 is reactive to C19ORF80 in Human, Mouse, Rat
Reconstitution
Observed Molecular Weight
68 kDa
Calculated molecular weight
22105 MW
Background of Angiopoietin-like protein 8/Betatrophin
The Betatrophin protein, also known as the hepatocellular carcinoma-associated protein TD26, is an adipocyte- and liver-enriched insulin targeted gene that is thought to play a role in lipid metabolism be regulating serum triglyceride levels (1,2). Betatrophin is closely related to the angiopoietin-like (ANGPTL) protein family. Betatrophin mRNA increases in the cold environment and after treatment with a high-fat diet, while its mRNA levels decrease in response to fasting, suggesting that it may play a role in mediating thermogenesis and energy homeostasis (3).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
A02471-1 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
Betatrophin antibody can be used for detection of Betatrophin by Western blot at 1 - 2 μg/ml. Antibody can also be used for Immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in rat samples; Immunohistochemistry in mouse and rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
Click image to see more details
Western blot analysis of Betatrophin in rat liver tissue lysate with Betatrophin antibody at (A) 1 and (B) 2 μg/ml.
Click image to see more details
Immunohistochemistry of Betatrophin in mouse liver tissue with Betatrophin antibody at 5 μg/mL.
Click image to see more details
Immunohistochemistry of Betatrophin in rat liver tissue with Betatrophin Antibody at 5 μg/mL.
Click image to see more details
Immunofluorescence of Betatrophin in rat liver tissue with Betatrophin Antibody at 20 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For C19ORF80 (Source: Uniprot.org, NCBI)
Gene Name
C19ORF80
Full Name
Angiopoietin-like protein 8
Weight
22105 MW
Superfamily
ANGPTL8 family
Alternative Names
RIFL, TD26, ANGPTL8, PRO1185, PVPA599, Angptl8, UNQ599/PRO1185, Betatrophin, Angiopoietin-like protein 8 ANGPTL8 C19orf80, PRO1185, PVPA599, RIFL, TD26 angiopoietin like 8 angiopoietin-like protein 8|betatrophin variant 1|betatrophin variant 2|hepatocellular carcinoma-associated gene TD26|hepatocellular carcinoma-associated protein TD26|lipasin|refeeding-induced fat and liver protein
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on C19ORF80, check out the C19ORF80 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for C19ORF80: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Betatrophin ANGPTL8 Antibody (A02471-1)
Loading publications
Recommended Resources
Here are featured tools and databases that you might find useful.
- Boster's Pathways Library
- Protein Databases
- Bioscience Research Protocol Resources
- Data Processing & Analysis Software
- Photo Editing Software
- Scientific Literature Resources
- Research Paper Management Tools
- Molecular Biology Software
- Primer Design Tools
- Bioinformatics Tools
- Phylogenetic Tree Analysis
Customer Reviews
Have you used Anti-Betatrophin ANGPTL8 Antibody?
Submit a review and receive an Amazon gift card.
- $30 for a review with an image
0 Reviews For Anti-Betatrophin ANGPTL8 Antibody
Customer Q&As
Have a question?
Find answers in Q&As, reviews.
Can't find your answer?
Submit your question
